{"_buckets": {"deposit": "fb109c06-e6e3-40c3-bac5-c82da5a58d99"}, "_deposit": {"id": "33729", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "33729"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00033729"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Feasibility of M30 antibody for the Histopathologic Detection of Apoptosis : Comparative study with TUNEL Method"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-09", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8-9", "bibliographicPageEnd": "313", "bibliographicPageStart": "307", "bibliographicVolumeNumber": "132", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c "}, {"bibliographic_title": "NIIGATA MEDICAL JOURNAL", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u691c\u7d22\u306b\u306f, caspase\u7cfb\u9175\u7d20\u306e\u6d3b\u6027\u5316\u306b\u3088\u308a\u751f\u3058\u305f\u65ad\u7247\u5316DNA\u3092\u8a8d\u8b58\u3059\u308bTU NEL \u6cd5\u304c\u6c4e\u7528\u3055\u308c\u3066\u304d\u305f\u3057\u304b\u3057TUNEL\u6cd5\u306b\u306f\u7d30\u80de\u58ca\u6b7b\u3082\u8a8d\u8b58\u3059\u308b\u3053\u3068\u3084\uff0c\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u6307\u6570(apoptotic index: A.I.)\u3092\u7b97\u5b9a\u3059\u308b\u969b\uff0c\u3069\u306e\u5927\u304d\u3055\u306e\u65ad\u7247\u6838\u307e\u3067\u3092TUNEL\u967d\u6027\u3068\u3068\u308b\u304b\u306b\u3064\u3044\u3066\u306e\u57fa\u6e96\u304c\u7121\u3044\u3053\u3068\u304b\u3089\uff0cA.I.\u306b\u306f\u5ba2\u89b3\u6027\u304c\u4e4f\u3057\u3044\uff0c\u7b49\u306e\u554f\u984c\u70b9\u304c\u3042\u3063\u305f\uff0eM30 cytoDEATH\u514d\u75ab\u67d3\u8272\u306f\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u969b\u306bcaspase 3\u3067\u5207\u65ad\u3055\u308c\u308b\u7d30\u80de\u9aa8\u683c\u86cb\u767dCK18\u306e\u30a8\u30d4\u30c8\u30fc\u30d7\u3092\u7279\u7570\u7684\u306b\u8a8d\u8b58\u3059\u308b\u65b9\u6cd5\u3067\u3042\u308a\uff0c\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u65e9\u671f\u6bb5\u968e\u306e\u7d30\u80de\u8cea\u306b\u967d\u6027\u3068\u306a\u308a\uff0c\u58ca\u6b7b\u7d30\u80de\u306b\u306f\u67d3\u8272\u3055\u308c\u306a\u3044\u3053\u3068\u304b\u3089\uff0cA.I.\u306e\u5ba2\u89b3\u7684\u7b97\u5b9a\u306b\u6709\u7528\u306a\u65b9\u6cd5\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\uff0e\u672c\u7814\u7a76\u3067\u306f\uff0c\u5185\u8996\u93e1\u7684\u5207\u9664\u30db\u30eb\u30de\u30ea\u30f3\u56fa\u5b9a\u5927\u8178\u817a\u816b27\u75c5\u5909\u3092\u5bfe\u8c61\u306b, M30 cytoDEATH\u514d\u75ab\u67d3\u8272\u3068TUNEL\u6cd5\u306e\u6bd4\u8f03\u3092\u884c\u3046\u3053\u3068\u3067, M30 cytoDEATH\u514d\u75ab\u67d3\u8272\u304c\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u691c\u7d22\u306b\u6709\u7528\u304b\u3069\u3046\u304b\u306b\u3064\u3044\u3066\u691c\u8a0e\u3057\u305f\uff0e\u30d1\u30e9\u30d5\u30a3\u30f3\u30d6\u30ed\u30c3\u30af\u304b\u3089\u306e3\u03bcm\u5207\u7247\u306bHE\u67d3\u8272\uff0cM30 cytoDEATH\u514d\u75ab\u67d3\u8272\uff0cTUNEL\u6cd5\u3092\u65bd\u884c\u3057\u305f. M30 cytoDEATH\u514d\u75ab\u67d3\u8272\u3067\u306f\uff0c\u7d30\u80de\u8cea\u5168\u4f53\u304c\u3073\u307e\u3093\u6027\u3082\u3057\u304f\u306f\u9846\u7c92\u72b6\u306b\u67d3\u8272\u3055\u308c\u308b\u3082\u306e\u3092\u967d\u6027\uff0cTUNEL \u6cd5\u3067\u306f\uff0c\u8336\u8272\u306b\u767a\u8272\u3055\u308c\u305f\u9846\u7c92\u72b6\u3082\u3057\u304f\u306f\u70b9\u72b6\u967d\u6027\u7269\u3059\u3079\u3066\u3092TUNEL\u967d\u6027(All TUNEL\u967d\u6027\uff09\u3068\u3057\uff0c\u305d\u308c\u3089\u306e\u4e2d\u3067\u5f62\u614b\u5b66\u7684\u306b\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u5c0f\u4f53(apoptotic body: AB)\u3068\u5224\u5b9a\u3067\u304d\u308b\u3082\u306e\u3092AB TUNEL\u967d\u6027\uff0c\u3068\u3057\u305f\uff0eTUNEL\u6cd5\u306eAll TUNEL\u967d\u6027\u3067\u306f\uff0c\u5c0f\u70b9\u72b6\u967d\u6027\u7269\u304c\u8907\u6570\u96c6\u65cf\u3057\u3066\u5b58\u5728\u3059\u308b\u3082\u306e\u306e\u660e\u3089\u304b\u306a\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u5c0f\u4f53\u3092\u5f62\u6210\u3057\u306a\u3044\u3082\u306e\uff0c\u5c0f\u578b\u70b9\u72b6\u967d\u6027\u7269\u304c\u817a\u7ba1\u751a\u5e95\u5074\u306b\u3073\u307e\u3093\u6027\u306b\u51fa\u73fe\u3059\u308b\u3082\u306e\u306a\u3069\u304c\u307f\u3089\u308c\u305f. M30 cytoDEATH\u514d\u75ab\u67d3\u8272\u3067\u306f\uff0c\u967d\u6027\u5224\u5b9a\u306b\u82e6\u616e\u3059\u308b\u3082\u306e\u306f\u5c11\u306a\u304b\u3063\u305f. 24\u4f8b\u306e\u817a\u816b\u304b\u308954\u9818\u57df\u3092\u62bd\u51fa\u3057\uff0c\u5404\u9818\u57ce\u306eA.I.\u3092\u7b97\u5b9a\u3057\u305f. All TUNEL\u967d\u6027\u306eA.I.(All TUNEL A.I.) \u306f9.49\u58eb0.87%, AB TUNEL\u967d\u6027\u306eA.I.(AB TUNEL A.I.)\u306f3.73\u58eb0.29%, M30 cytoDEATH \u514d\u75ab\u67d3\u8272\u306eA.I.(M30 A.I.)\u306f2.53\u58eb0.35%\u3067\uff0c\u305d\u308c\u305e\u308c\u306e\u9593\u306b\u306f\u6709\u610f\u5dee\u304c\u3042\u3063\u305f( P\u003c0.001). M30 A.I.\u306f, All TUNEL A.I., AB TUNEL A.I. \u306e\u3044\u305a\u308c\u3068\u3082\u6709\u610f\u306b\u76f8\u95a2\u3057\u3066\u3044\u305f( P\u003c0.001). \u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089,M30 cytoDEATH\u514d\u75ab\u67d3\u8272\u306f\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3092\u6b63\u78ba\u306b\u5224\u5b9a\u3057\u3066\u304a\u308a\uff0c\u305d\u306e\u5224\u5b9a\u306e\u5bb9\u6613\u3055\u3084\u5ba2\u89b3\u6027\u306e\u89b3\u70b9\u304b\u3089\uff0c\u3053\u308c\u307e\u3067\u6c4e\u7528\u3055\u308c\u3066\u304d\u305fTUNEL\u6cd5\u306b\u4ee3\u308f\u308a, \u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u691c\u7d22\u306b\u6709\u7528\u306a\u65b9\u6cd5\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u308b\uff0e", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "50710", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "SANO, Tomoe"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u4f50\u91ce, \u77e5\u6c5f"}], "nameIdentifiers": [{"nameIdentifier": "50709", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "132(8-9)_307-313.pdf", "filesize": [{"value": "5.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 5200000.0, "url": {"url": "https://niigata-u.repo.nii.ac.jp/record/33729/files/132(8-9)_307-313.pdf"}, "version_id": "822c4b82-6332-48c9-b964-7484e825a7f7"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9", "subitem_subject_scheme": "Other"}, {"subitem_subject": "M30", "subitem_subject_scheme": "Other"}, {"subitem_subject": "TUNEL \u6cd5", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u514d\u75ab\u67d3\u8272", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u691c\u7d22\u306b\u304a\u3051\u308bM30 cytoDEATH\u514d\u75ab\u67d3\u8272\u306e\u6709\u7528\u6027\u306b\u3064\u3044\u3066 : TUNEL\u6cd5\u3068\u306e\u6bd4\u8f03\u691c\u8a0e", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u691c\u7d22\u306b\u304a\u3051\u308bM30 cytoDEATH\u514d\u75ab\u67d3\u8272\u306e\u6709\u7528\u6027\u306b\u3064\u3044\u3066 : TUNEL\u6cd5\u3068\u306e\u6bd4\u8f03\u691c\u8a0e"}, {"subitem_title": "Feasibility of M30 antibody for the Histopathologic Detection of Apoptosis : Comparative study with TUNEL Method", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1992"], "permalink_uri": "http://hdl.handle.net/10191/00051551", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2020-04-09"}, "publish_date": "2020-04-09", "publish_status": "0", "recid": "33729", "relation": {}, "relation_version_is_last": true, "title": ["\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306e\u75c5\u7406\u7d44\u7e54\u5b66\u7684\u691c\u7d22\u306b\u304a\u3051\u308bM30 cytoDEATH\u514d\u75ab\u67d3\u8272\u306e\u6709\u7528\u6027\u306b\u3064\u3044\u3066 : TUNEL\u6cd5\u3068\u306e\u6bd4\u8f03\u691c\u8a0e"], "weko_shared_id": 2}