{"_buckets": {"deposit": "070a88e4-f273-49b1-a4c1-643b016c8699"}, "_deposit": {"id": "32159", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "32159"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00032159"}, "item_6_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "A study of image quality improvement and development of novel method for evaluating ischemia in brain 4D CT"}]}, "item_6_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2019-03-25", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "73", "bibliographicPageStart": "1", "bibliographic_titles": [{}]}]}, "item_6_date_granted_51": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u5e74\u6708\u65e5", "attribute_value_mlt": [{"subitem_dategranted": "2019-03-25"}]}, "item_6_degree_grantor_49": {"attribute_name": "\u5b66\u4f4d\u6388\u4e0e\u6a5f\u95a2", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_name": "\u65b0\u6f5f\u5927\u5b66"}]}]}, "item_6_degree_name_48": {"attribute_name": "\u5b66\u4f4d\u540d", "attribute_value_mlt": [{"subitem_degreename": "\u535a\u58eb\uff08\u4fdd\u5065\u5b66\uff09"}]}, "item_6_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "  \u672c\u7814\u7a76\u306e\u76ee\u7684\u306f\uff0c\u982d\u90e8\u56db\u6b21\u5143computed tomography (four dimensional CT: 4DCT)\u306b\u304a\u3044\u3066\u753b\u8cea\u3092\u6539\u5584\u3059\u308b\u624b\u6cd5\u306e\u6709\u7528\u6027\u3092\u78ba\u8a8d\u3059\u308b\u3053\u3068\u3067\u3042\u308b\uff0e\u307e\u305f\uff0c\u65b0\u305f\u306a\u865a\u8840\u8a55\u4fa1\u624b\u6cd5\u306e\u958b\u767a\u3068\u6709\u7528\u6027\u3092\u691c\u8a3c\u3059\u308b\u3053\u3068\u3067\u3042\u308b\uff0e\u9020\u5f71\u5264\u3092\u7528\u3044\u3066\u8840\u884c\u52d5\u614b\u3092\u89b3\u5bdf\u3059\u308b4D-CT\u8840\u7ba1\u9020\u5f71 (4D-CT Angiography: 4D-CTA) \u3067\u306f\uff0c\u8133\u52d5\u8108\u306e\u8840\u884c\u52d5\u614b\u3068\u5074\u526f\u8840\u884c\u52d5\u614b\u306e\u89b3\u5bdf\u304c\u5bb9\u6613\u306b\u306a\u308a\uff0c\u865a\u8840\u6027\u8133\u8840\u7ba1\u969c\u5bb3\u306e\u8a3a\u65ad\u306b\u6709\u7528\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3059\u308b\uff0e\u3057\u304b\u3057\uff0c4D-CT\u306f\u9023\u7d9a\u3067\u64ae\u5f71\u3092\u3059\u308b\u305f\u3081\uff0c\u653e\u5c04\u7dda\u91cf\u3092\u6291\u3048\u305f\u64ae\u5f71\u6761\u4ef6\u304c\u4e00\u822c\u7684\u3067\u3042\u308b\uff0e\u81e8\u5e8a\u306b\u304a\u3051\u308b\u30d7\u30ed\u30c8\u30b3\u30fc\u30eb\u306e\u8a2d\u5b9a\u306b\u3064\u3044\u3066\u306f\uff0c\u3088\u308a\u4f4e\u3044\u653e\u5c04\u7dda\u91cf\u306e\u8a2d\u5b9a\u304c\u63a8\u5968\u3055\u308c\u308b\uff0e\u3057\u305f\u304c\u3063\u3066\uff0c\u753b\u50cf\u30ce\u30a4\u30ba\u304c\u4ed6\u306eCT\u691c\u67fb\u3068\u6bd4\u8f03\u3057\u3066\u591a\u3044\u3053\u3068\u3082\u7279\u5fb4\u3067\u3042\u308b\uff0e\u753b\u50cf\u30ce\u30a4\u30ba\u306f\uff0c\u5fae\u7d30\u306a\u8840\u7ba1\u306e\u89b3\u5bdf\u306b\u304a\u3044\u3066\u59a8\u3052\u306b\u306a\u308b\u305f\u3081\uff0c\u3088\u308a\u5c11\u306a\u3044\u3053\u3068\u304c\u671b\u307e\u3057\u3044\uff0e\u3064\u307e\u308a\uff0c\u753b\u50cf\u30ce\u30a4\u30ba\u306e\u4f4e\u6e1b\u306f4D-CT\u306b\u304a\u3051\u308b\u76ae\u8cea\u679d\u306e\u8a55\u4fa1\u306b\u3068\u3063\u3066\u91cd\u8981\u306a\u554f\u984c\u3067\u3042\u308b\uff0e\u3053\u306e\u554f\u984c\u306e\u89e3\u6c7a\u306e\u305f\u3081\uff0c4D-CT\u306e\u7279\u6027\u3092\u6d3b\u304b\u3057\uff0c\u753b\u50cf\u3092\u6642\u9593\u8ef8\u3067\u52a0\u7b97\u5e73\u5747\u3057\u3066\u753b\u50cf\u30ce\u30a4\u30ba\u3092\u4f4e\u6e1b\u3055\u305b\u308btemporal average (TA) \u6cd5\u3092\u8003\u6848\u3057\u305f\uff0eTA\u6cd5\u306e\u6709\u7528\u6027\u306b\u3064\u3044\u3066\uff0c\u540c\u3058\u304f\u753b\u50cf\u30ce\u30a4\u30ba\u3092\u4f4e\u6e1b\u3055\u305b\u308b\u5225\u624b\u6cd5\u3092\u5bfe\u8c61\u306b\uff0c\u982d\u84cb\u5185\u5fae\u7d30\u8840\u7ba1\u306e\u63cf\u51fa\u306b\u3064\u3044\u306614\u75c7\u4f8b\u306e\u8133\u8840\u7ba14D-CT\u3092\u7528\u3044\u3066\u6bd4\u8f03\u3057\u305f\uff0e\u305d\u306e\u7d50\u679c\uff0cTA\u6cd5\u306f\u30ce\u30a4\u30ba\u3068\u7a7a\u9593\u5206\u89e3\u80fd\u306b\u3064\u3044\u3066\u826f\u597d\u306a\u30d0\u30e9\u30f3\u30b9\u3092\u3082\u305f\u3089\u3057\uff0c\u76ae\u8cea\u679d\u306e\u8996\u8a8d\u6027\u3092\u9855\u8457\u306b\u6539\u5584\u3057\u305f\uff0e\n  \u6b21\u306b\uff0c4D-CT \u306e\u753b\u50cf\u3092\u7528\u3044\u3066\u65b0\u305f\u306a\u865a\u8840\u8a55\u4fa1\u624b\u6cd5\u306e\u958b\u767a\u3068\u6709\u7528\u6027\u3092\u691c\u8a3c\u3057\u305f\uff0eCT\u691c\u67fb\u306b\u304a\u3051\u308b\u8133\u8840\u6d41\u8a55\u4fa1\u306f\uff0c\u30e8\u30fc\u30c9\u9020\u5f71\u5264\u306e\u8133\u5185\u5faa\u74b0\u3092\u3042\u3089\u308f\u3059CT Perfusion (CTP) \u304c\u5e83\u304f\u81e8\u5e8a\u5fdc\u7528\u3055\u308c\u3066\u3044\u308b\uff0e\u305d\u306e\u89e3\u6790\u8a08\u7b97\u306f\uff0c\u9020\u5f71\u5264\u304c\u8133\u7d44\u7e54\u306b\u5230\u9054\u3057\u3066\u304b\u3089\u901a\u904e\u3059\u308b\u307e\u3067\u306e\u6642\u9593\u3067\u7406\u8ad6\u4e0a\uff0c\u89e3\u6790\u3055\u308c\u308b\uff0e\u89e3\u6790\u306f\u6b63\u5e38\u8840\u7ba1\u3092\u57fa\u6e96\u3068\u3057\u3066\u5168\u8133\u7d44\u7e54\u306e\u9020\u5f71\u5264\u306e\u6d41\u308c\u304c\u8a55\u4fa1\u3055\u308c\u308b\uff0e\u3057\u305f\u304c\u3063\u3066\uff0c\u981a\u90e8\u306a\u3069\u8fd1\u4f4d\u8840\u7ba1\u306b\u72ed\u7a84\u306a\u3069\u304c\u5b58\u5728\u3059\u308b\u5834\u5408\uff0c\u982d\u84cb\u5185\u306b\u3082\u3068\u3082\u3068\u5b58\u5728\u3059\u308b\u6b63\u5e38\u8840\u7ba1\u3068\u306e\u9020\u5f71\u5264\u306e\u6d41\u308c\u306e\u5dee\u3092\uff0c\u66f4\u306b\u52a9\u9577\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e\u3057\u305f\u304c\u3063\u3066\uff0c\u89e3\u6790\u6cd5\u306b\u306f\u3055\u307e\u3056\u307e\u306a\u8af8\u554f\u984c\u306b\u5bfe\u5fdc\u3057\u305f\u624b\u6cd5\u304c\u63d0\u5531\u3055\u308c\u308b\uff0e\u3057\u304b\u3057\uff0c\u89e3\u6790\u6cd5\u306e\u591a\u3055\u306f\uff0c\u704c\u6d41\u753b\u50cf\u3068\u3057\u3066\u7570\u306a\u308b\u7d50\u679c\u3092\u793a\u3059\u3053\u3068\u3082\u8003\u3048\u3089\u308c\u308b\uff0e\u7533\u8acb\u8005\u306f\u89e3\u6790\u6cd5\u306b\u4f9d\u5b58\u3057\u306a\u3044\u65b0\u305f\u306a\u704c\u6d41\u8a55\u4fa1\u7528\u753b\u50cf(phase ratio image map: PI map) \u3092\u8003\u6848\u3057\u305f\uff0ePI map \u306e\u6709\u7528\u6027\u306b\u3064\u3044\u3066\uff0c\u6162\u6027\u671f\u306e\u865a\u8840\u6027\u8133\u8840\u7ba1\u969c\u5bb320\u75c7\u4f8b\u306e\u60a3\u5074\u5065\u5074\u6bd4\u306b\u304a\u3044\u3066PI map\u3068positron emission tomography-cerebral blood flow (PET-CBF)\u3092\u6bd4\u8f03\u3057\u305f\uff0e\u305d\u306e\u7d50\u679c\uff0cPI map\u306fCTP\u306e\u704c\u6d41\u30de\u30c3\u30d7\u3088\u308a\u3082PET-CBF\u3068\u5f37\u3044\u76f8\u95a2\u3092\u793a\u3057\u305f\uff0e\u3057\u305f\u304c\u3063\u3066\uff0cPI map\u306f\u704c\u6d41\u8a55\u4fa1\u7528\u753b\u50cf\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u305f\uff0e\n  \u6025\u6027\u671f\u8133\u865a\u8840\u306b\u304a\u3044\u3066Multiphase CTA (MP-CTA)\u306f\uff0c\u982d\u84cb\u5185\u8840\u7ba1\u3092\u8fc5\u901f\u306b\u753b\u50cf\u5316\u3059\u308b\u624b\u6cd5\u3068\u3057\u3066\u78ba\u7acb\u3055\u308c\u308b\uff0e\u307e\u305f\uff0c\u5074\u526f\u8840\u884c\u3092\u8a55\u4fa1\u3059\u308b\u8fc5\u901f\u304b\u3064\u4f7f\u3044\u3084\u3059\u3044\u753b\u50cf\u8a3a\u65ad\u30c4\u30fc\u30eb\u3067\u3042\u308b\uff0e\u982d\u84cb\u5185\u8840\u7ba1\u3092\u585e\u6813\u5b50\u304c\u9589\u585e\u3059\u308b\u5fc3\u539f\u6027\u8133\u585e\u6813\u75c7\u306e\u8840\u6813\u56de\u53ce\u7642\u6cd5\u3067\u306f\uff0c\u65e9\u671f\u306e\u6700\u958b\u901a\u3067\u3042\u308b\u307b\u3069\u4e88\u5f8c\u826f\u597d\u306a\u78ba\u7387\u304c\u9ad8\u3044\u3068\u3055\u308c\u308b\uff0e\u3057\u305f\u304c\u3063\u3066\uff0c\u982d\u84cb\u5185\u8840\u7ba1\u306e\u753b\u50cf\u5316\u306f\u8fc5\u901f\u304b\u3064\u6b63\u78ba\u3067\u3042\u308b\u3053\u3068\u304c\u671b\u307e\u3057\u3044\uff0eMP-CTA\u3067\u306f\uff0c\u8840\u7ba1\u63cf\u51fa\u9818\u57df\u306e\u6b20\u640d\u304c\u5e83\u6c4e\u3067\u306f\u306a\u3044\u5834\u5408\u3092\u518d\u958b\u901a\u3067\u4e88\u5f8c\u304c\u826f\u597d\u3068\u306a\u308a\u5f97\u308b\u60a3\u8005\u3068\u3057\u3066\u53d6\u6271\u3063\u3066\u3044\u305f\uff0eMP-CTA\u3067\u306f\u65e9\u671f\u76f8\u3068\u9045\u5ef6\u76f8\u306b\u3088\u3063\u3066\uff0c\u982d\u84cb\u5185\u8840\u7ba1\u306e\u6700\u672b\u68a2\u3067\u3042\u308b\u8133\u8edf\u819c\u52d5\u8108\u306e\u63cf\u51fa\u3068\u9020\u5f71\u5f37\u5ea6\u306e\u5de6\u53f3\u5dee\u304c\uff0c\u7d4c\u6642\u7684\u306b\u3082\u8a55\u4fa1\u53ef\u80fd\u3067\u3042\u308b\uff0e\u3053\u3046\u3057\u305f\u9045\u5ef6\u76f8\u306e\u4ed8\u52a0\u306f\uff0c\u8a73\u7d30\u306a\u75c5\u614b\u8a55\u4fa1\u306b\u304a\u3044\u3066\u6709\u7528\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u308b\uff0e\u6025\u6027\u671f\u8133\u865a\u8840\u306b\u304a\u3044\u3066\u8133\u6897\u585e\u9818\u57df\u306e\u753b\u50cf\u7684\u306a\u8a55\u4fa1\u306f\uff0c\u6838\u78c1\u6c17\u5171\u9cf4\u753b\u50cf\u306e\u62e1\u6563\u5f37\u8abf\u50cf\u3084\u5358\u7d14CT\uff0c\u307e\u305fCTP\u306ecerebral blood volume (CBV)\u304c\u4e00\u822c\u7684\u3067\u3042\u308b\uff0e\u4e00\u65b9\uff0cCTA \u3067\u306f\u982d\u84cb\u5185\u8840\u7ba1\u306e\u6b20\u640d\u9818\u57df\u304b\u3089\uff0c\u8133\u6897\u585e\u9818\u57df\u3092\u4e88\u6e2c\u305b\u3056\u308b\u3092\u5f97\u306a\u3044\uff0eMPCTA\u3067\u5ba2\u89b3\u7684\u306b\u8133\u6897\u585e\u9818\u57df\u306e\u8a55\u4fa1\u304c\u53ef\u80fd\u306a\u3089\u3070\uff0c\u3088\u308a\u6b63\u78ba\u306a\u75c5\u614b\u8a55\u4fa1\u306e\u624b\u6cd5\u3068\u3057\u3066\u60a3\u8005\u4e88\u5f8c\u306e\u5411\u4e0a\u306b\u5bc4\u4e0e\u3059\u308b\u3067\u3042\u308d\u3046\uff0e\u3053\u306e\u554f\u984c\u70b9\u306e\u89e3\u6c7a\u7b56\u3068\u3057\u3066\uff0cPI map\u3092\u5fdc\u7528\u3057\u305f\u8133\u6897\u585e\u9818\u57df\u306e\u7279\u5b9a\u3092\u7c21\u4fbf\u306b\u884c\u3046\u3053\u3068\u304c\u53ef\u80fd\u306a\u65b0\u3057\u3044\u5f8c\u51e6\u7406\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0 (phase ratio map: PR map) 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