{"_buckets": {"deposit": "5976673a-4520-4887-9a8b-f77e949b4558"}, "_deposit": {"id": "25689", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25689"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00025689", "sets": ["456", "1313"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2002-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "26", "bibliographicPageStart": "17", "bibliographicVolumeNumber": "32", "bibliographic_titles": [{"bibliographic_title": "新潟歯学会雑誌"}, {"bibliographic_title": "新潟歯学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Manganase- and copper-zinc superoxide dismutases (Mn- and Cu/Zn-SODs) are representative enzymes for scavenging superoxide radicals, which are considered to cause aging and cell damage. Our recent study has demonstrated the localization of Mn-and Cu/Zn-SOD proteins as well as the expression of Mn-and Cu/Zn-SOD mRNAs in all types of duct cells-and not in acinar cells- in the submandibular gland of adult rats. However, the expression of these two enzymes remains unclear in rat developing submandibular gland. Thus, the present study examined the expression of Mn- and Cu/Zn-SODs in the submandibular gland of rats aged from embryonic 18 days to postnatal 8 weeks by an immunohistochemical technique using specific antisera. The deparaffinized sections were processed for the avidin-biotin complex method. On the prenatal 18th day, a small number of epithelial duct cells and cells in acini exhibited Cu/Zn-SOD-immunoreactivity, but they did not show any immunoreactions for Mn-SODs. From postnatal 1day to 1 week, Mn- and Cu/Zn-SOD-immunoreactivities were found in both the duct cells and the cells in acini. This drastic change in the expression of Mn- and Cu/Zn-SOD-immunoreactivities between prenatal and postnatal periods was believed to relate to the commencement of pulmonary respiration due to oxygen exposure. After 2 weeks, however, the cells in the acini lost Mn- and Cu/Zn-SOD-immunoreactions, though the duct cells retained them, suggesting that the duct cells in the mature submandibular gland exhibit greater resistance against oxidative stress than do the acinar cells.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟歯学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN0018300X", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "03850153", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Arimatsu, Mikiko"}], "nameIdentifiers": [{"nameIdentifier": "151453", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Maeda, Takeyasu"}], "nameIdentifiers": [{"nameIdentifier": "151454", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kawano, Yoshiro"}], "nameIdentifiers": [{"nameIdentifier": "151455", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "NS_32(2)_17-26.pdf", "filesize": [{"value": "5.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 5500000.0, "url": {"label": "NS_32(2)_17-26.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/25689/files/NS_32(2)_17-26.pdf"}, "version_id": "ce8a0442-0a8b-4a93-abfc-9e9f32e895d8"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "superoxide dismutase", "subitem_subject_scheme": "Other"}, {"subitem_subject": "submandibular gland", "subitem_subject_scheme": "Other"}, {"subitem_subject": "development", "subitem_subject_scheme": "Other"}, {"subitem_subject": "immunohistochemistry", "subitem_subject_scheme": "Other"}, {"subitem_subject": "rat", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Expression of Immunoreactivities for Manganese and Copper/Zinc Superoxide Dismutases(Mn-and Cu/Zn-SODs)During Development of the Rat Submandibular Gland", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Expression of Immunoreactivities for Manganese and Copper/Zinc Superoxide Dismutases(Mn-and Cu/Zn-SODs)During Development of the Rat Submandibular Gland"}, {"subitem_title": "Expression of Immunoreactivities for Manganese and Copper/Zinc Superoxide Dismutases(Mn-and Cu/Zn-SODs)During Development of the Rat Submandibular Gland", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1313"], "permalink_uri": "http://hdl.handle.net/10191/23241", "pubdate": {"attribute_name": "公開日", "attribute_value": "2013-08-27"}, "publish_date": "2013-08-27", "publish_status": "0", "recid": "25689", "relation": {}, "relation_version_is_last": true, "title": ["Expression of Immunoreactivities for Manganese and Copper/Zinc Superoxide Dismutases(Mn-and Cu/Zn-SODs)During Development of the Rat Submandibular Gland"], "weko_shared_id": null}