{"_buckets": {"deposit": "4bf3cd31-4f9c-4860-9e99-60181e4bc0d4"}, "_deposit": {"id": "25663", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "25663"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00025663"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Clinical evaluation of platelet-rich plasma combined with porous hydroxyapatite graft for the treatment of intrabony periodontal defects: 1-year result"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2003-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "94", "bibliographicPageStart": "87", "bibliographicVolumeNumber": "33", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u6b6f\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u6b6f\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "The purpose of this study was to evaluate the effect of a platelet-rich plasma (PRP) in combination with a biodegradable ceramics, porous hydroxyapatite granules (HA) in periodontal regeneration of angular bone defects in humans. Twenty patients participated, each contributing at least 1 defect site, which exhibited a pocket probing depth (PPD) of \u2267 6mm, a clinical attachment level (CAL) of \u2267 6mm, and was positive for bleeding on probing (BOP) following initial therapy. Twenty angular bone defects were filled with PRP + HA. The observation period was 1 year and included measurements of plaque, gingivitis, PPD, CAL, soft tissue recession, and bone level as assessed from standardized radiographs. Data were statistically analyzed using the Wilcoxon-signed ranks test (a=0.05). At the 1 year evaluation visit, gingival index and bleeding on probing was less 0.10\u00b10.31 and 0.15\u00b10.37 compared to the baseline, 0.85\u00b10.67 and 0.95\u00b10.22, respectively (p\u003c0.01). The residual PPD and CAL were reduced to 3.15\u00b10.88mm (PPD) and 4.85\u00b11.50mm (CAL) with a CAL gain of 2.90\u00b12.13mm at 1 year (P\u003c0.001). The depth of radiographic bone defect was decreased to 2.65\u00b10.99mm at 1 year from 6.40\u00b10.88mm at baseline (p\u003c0.0001). These findings indicate that angular bone defects can be successfully treated with PRP in combination with HA.", "subitem_description_type": "Abstract"}, {"subitem_description": 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