{"created":"2021-03-01T06:31:09.696357+00:00","id":25663,"links":{},"metadata":{"_buckets":{"deposit":"4bf3cd31-4f9c-4860-9e99-60181e4bc0d4"},"_deposit":{"id":"25663","owners":[],"pid":{"revision_id":0,"type":"depid","value":"25663"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00025663","sets":["432:1291:1292:1311","453:456"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Clinical evaluation of platelet-rich plasma combined with porous hydroxyapatite graft for the treatment of intrabony periodontal defects: 1-year result"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"94","bibliographicPageStart":"87","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"新潟歯学会雑誌"},{"bibliographic_title":"新潟歯学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The purpose of this study was to evaluate the effect of a platelet-rich plasma (PRP) in combination with a biodegradable ceramics, porous hydroxyapatite granules (HA) in periodontal regeneration of angular bone defects in humans. Twenty patients participated, each contributing at least 1 defect site, which exhibited a pocket probing depth (PPD) of ≧ 6mm, a clinical attachment level (CAL) of ≧ 6mm, and was positive for bleeding on probing (BOP) following initial therapy. Twenty angular bone defects were filled with PRP + HA. The observation period was 1 year and included measurements of plaque, gingivitis, PPD, CAL, soft tissue recession, and bone level as assessed from standardized radiographs. Data were statistically analyzed using the Wilcoxon-signed ranks test (a=0.05). At the 1 year evaluation visit, gingival index and bleeding on probing was less 0.10±0.31 and 0.15±0.37 compared to the baseline, 0.85±0.67 and 0.95±0.22, respectively (p<0.01). The residual PPD and CAL were reduced to 3.15±0.88mm (PPD) and 4.85±1.50mm (CAL) with a CAL gain of 2.90±2.13mm at 1 year (P<0.001). The depth of radiographic bone defect was decreased to 2.65±0.99mm at 1 year from 6.40±0.88mm at baseline (p<0.0001). These findings indicate that angular bone defects can be successfully treated with PRP in combination with HA.","subitem_description_type":"Abstract"},{"subitem_description":"多血小板血漿と吸収性人工骨移植材である多孔性ハイドロキシアパタイト顆粒を混合した移植材を作製し、歯周骨内欠損に対する臨床効果を検討した｡慢性歯周炎と診断され歯周基本治療後に少なくとも1カ所以上の部位に6mm以上の歯周ポケット深さ(PPD)とアタッチメントロス(CAL)を有し、かつエックス線写真で3mm以上の骨内欠損が認められた20名20部位を対象とした｡全層歯肉弁を形成･剥離して病巣部掻爬完了後にアルギン酸ナトリウムで活性化した多血小板血漿(PRP)と多孔性ハイドロキシアパタイト顆粒(HA)の混合移植材(PRP+HA)を填入し緊密に縫合した。術後1年日に臨床評価およびエックス線写真による評価を行いベースラインの値と比較検討した。gingival index(GI)およびbleeding on probing(BOP)はベースラインと比較して1年目において有意に低かった(GI:0.85±0.67→0.10±0.31、P＜０.01、BOP:0.95±0.22→0.15±0.37、P＜O.01)。 pocket probing depth(PPD)およびclinical attachment level(CAL)はベースラインと比較して1年目において有意に低かった(PPD:7.35±1.87mm→3.15±0.88mm、p＜0.001、CAL:7.75±1.89mm→4.85±1.50mm、p<0.001)｡エックス線的骨欠損深さはベースラインと比較して1年目において有意に浅かった（6.40±0.88mm→2.65±0.99mm、p＜0.0001)。以上より多血小板血漿と多孔性ハイドロキシアパタイト顆粒の混合移植材は術後1年の時点で臨床的に有効に作用したことが明らかとなった｡","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"151269","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Okuda, Kazuhiro"}]},{"nameIdentifiers":[{"nameIdentifier":"151270","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tai, Hideaki"}]},{"nameIdentifiers":[{"nameIdentifier":"151271","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Suzuki, Hironobu"}]},{"nameIdentifiers":[{"nameIdentifier":"151272","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sato, Tadashi"}]},{"nameIdentifiers":[{"nameIdentifier":"151273","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tanabe, Kiyoshi"}]},{"nameIdentifiers":[{"nameIdentifier":"151274","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nakasone, Naohiro"}]},{"nameIdentifiers":[{"nameIdentifier":"151275","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Saito, Yoshinori"}]},{"nameIdentifiers":[{"nameIdentifier":"151276","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yoshie, Hiromasa"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟歯学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN0018300X","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03850153","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"奥田, 一博"}],"nameIdentifiers":[{"nameIdentifier":"151261","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田井, 秀明"}],"nameIdentifiers":[{"nameIdentifier":"151262","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"鈴木, 啓展"}],"nameIdentifiers":[{"nameIdentifier":"151263","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"佐藤, 匡"}],"nameIdentifiers":[{"nameIdentifier":"151264","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"田辺, 清史"}],"nameIdentifiers":[{"nameIdentifier":"151265","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中曽根, 直弘"}],"nameIdentifiers":[{"nameIdentifier":"151266","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"齊藤, 宜則"}],"nameIdentifiers":[{"nameIdentifier":"151267","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"吉江, 弘正"}],"nameIdentifiers":[{"nameIdentifier":"151268","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"NS_33(2)_87-94.pdf","filesize":[{"value":"998.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"NS_33(2)_87-94.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/25663/files/NS_33(2)_87-94.pdf"},"version_id":"f4aac920-ce84-4941-a3b9-309bef4df91f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Plateｌet-rich plasma","subitem_subject_scheme":"Other"},{"subitem_subject":"多血小板血漿","subitem_subject_scheme":"Other"},{"subitem_subject":"Porous hydoxyapatite granules","subitem_subject_scheme":"Other"},{"subitem_subject":"多孔性ハイドロキシアパタイト顆粒","subitem_subject_scheme":"Other"},{"subitem_subject":"Tissue engineering","subitem_subject_scheme":"Other"},{"subitem_subject":"組織工学","subitem_subject_scheme":"Other"},{"subitem_subject":"Clinical evaluation","subitem_subject_scheme":"Other"},{"subitem_subject":"臨床効果","subitem_subject_scheme":"Other"},{"subitem_subject":"1-year result","subitem_subject_scheme":"Other"},{"subitem_subject":"1年予後","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"多血小板血漿と多孔性ハイドロキシアパタイト顆粒混合移植材の歯周骨内欠損に及ぼす臨床効果 : 1年予後","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"多血小板血漿と多孔性ハイドロキシアパタイト顆粒混合移植材の歯周骨内欠損に及ぼす臨床効果 : 1年予後"},{"subitem_title":"多血小板血漿と多孔性ハイドロキシアパタイト顆粒混合移植材の歯周骨内欠損に及ぼす臨床効果 : 1年予後","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1311"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-08-27"},"publish_date":"2013-08-27","publish_status":"0","recid":"25663","relation_version_is_last":true,"title":["多血小板血漿と多孔性ハイドロキシアパタイト顆粒混合移植材の歯周骨内欠損に及ぼす臨床効果 : 1年予後"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:55:39.685931+00:00"}