{"_buckets": {"deposit": "9c29c622-537b-4f7a-8d09-17b2411d3289"}, "_deposit": {"id": "24122", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "24122"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00024122", "sets": ["456", "1233"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Characterization of the surface antigens on human mononuclear cells to which anti-myelin associated glycoprotein (MAG) monoclonal antibodies bind"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1987-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "389", "bibliographicPageStart": "382", "bibliographicVolumeNumber": "101", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Three (GC-J4, MC-P2 and MC-P4) out of five murine monoclonal antibodies (mAbs) to myelin-associated glycoprotein (MAG) bound to human mononuclear cells (MNC). The results of the competitive inhibition assay suggested that MC-P2 and MC-P4 bind directly to or close to the Leu 7 epitope, and that GC-J4 binds to the epitope which is distinct from the Leu 7 epitope. The electrophoretic patterns of immunoprecipitates with GC-J4, MC-P2 and anti-Leu 7 from detergent lysates of surface labeled human MNC were very similar. The target molecules of anti-Leu 7, MC-P2 and GC-J4 have apparent molecular weights of 205, 170, 150, 135, 110, 85, 65 and 55 kDa, and they are monomeric or noncovalently associated proteins. The patterns of immunoprecipitates with MC-P4 were slightly different from those with anti-Leu 7 and MC-P2. The implications of these results are as follows: 1) The mAb with specificity to the carbohydrate part of MAG reacts with the Leu 7-reactive molecule on human MNC. 2) At least two epitopes detected by anti-MAG mAbs coexist on the surface molecules with various apparent molecular weights. 3) The fine antigenic specificity of MC-P4 is different from those of anti-Leu 7 or MC-P2.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "144533", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Arai, Motomi"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "荒井, 元美"}], "nameIdentifiers": [{"nameIdentifier": "144532", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "101(6)_382-389.pdf", "filesize": [{"value": "1.0 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1000000.0, "url": {"label": "101(6)_382-389.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/24122/files/101(6)_382-389.pdf"}, "version_id": "96f12fb7-bcf7-433c-bb63-c3775810d18e"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "monoclonal antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "myelin-associated glycoprotein", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mononuclear cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "surface marker", "subitem_subject_scheme": "Other"}, {"subitem_subject": "モノクローナル抗体", "subitem_subject_scheme": "Other"}, {"subitem_subject": "ミエリン糖蛋白", "subitem_subject_scheme": "Other"}, {"subitem_subject": "リンパ球", "subitem_subject_scheme": "Other"}, {"subitem_subject": "表面抗原", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "抗Myelin-associated glycoprotein(MAG)モノクローナル抗体と結合するヒトのリンパ球表面抗原の解析", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "抗Myelin-associated glycoprotein(MAG)モノクローナル抗体と結合するヒトのリンパ球表面抗原の解析"}, {"subitem_title": "抗Myelin-associated glycoprotein(MAG)モノクローナル抗体と結合するヒトのリンパ球表面抗原の解析", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1233"], "permalink_uri": "http://hdl.handle.net/10191/36481", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-01-07"}, "publish_date": "2016-01-07", "publish_status": "0", "recid": "24122", "relation": {}, "relation_version_is_last": true, "title": ["抗Myelin-associated glycoprotein(MAG)モノクローナル抗体と結合するヒトのリンパ球表面抗原の解析"], "weko_shared_id": null}