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Dipyridamole 負荷による, 肥大型心筋症及び高血圧性肥大心の冠血管予備能の検討 : ^<201>Tl 2回投与法を用いて
http://hdl.handle.net/10191/40585
http://hdl.handle.net/10191/40585231ca05c-b00f-49df-9a71-6f0c4184ee66
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
102(1)_38-47.pdf (2.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-04-04 | |||||
| タイトル | ||||||
| タイトル | Dipyridamole 負荷による, 肥大型心筋症及び高血圧性肥大心の冠血管予備能の検討 : ^<201>Tl 2回投与法を用いて | |||||
| タイトル | ||||||
| タイトル | Dipyridamole 負荷による, 肥大型心筋症及び高血圧性肥大心の冠血管予備能の検討 : ^<201>Tl 2回投与法を用いて | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Dipyridamole | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | coronary reserve | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | reactive hyperemia | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Hypertrophic cardiomyopathy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hypertensive heart disease | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Thallium-scintigraphy | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Assessment of the coronary reserve by dipyridamole loading : An experimental and clinical study | |||||
| 著者 |
里方, 美智子
× 里方, 美智子 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 142076 | |||||
| 姓名 | Satokata, Michiko | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In order to study the coronary reserve by dipyridamole loading, we compared the maximal flow induced by dipyridamole with the post-occlusion reactive hyperemia in the closed-chest dog. The coronary flow increased gradually by systemic administration of dipyridamole(0.5mg/kg)and reached to 97% of the peak reactive hyperemic flow at 5 minutes after the administration. Intracoronary nitroglycerin little affected the coronary flow at the time of the maximal flow. Dipyridamole loading can therefore induce a sustaining maximal flow and abnormal lesions in the large vessel or the microcirculation will be detected as the limited maximal flow following dipyridamole. In patients with cardiomyopathy (HCM) or hypertension (HT), the coronary reserve was assessed from the ratio of thallium (Tl) uptake in the two-successive administration method. The low value of the ratio was supposed to reflect a limited increase of coronary flow, i. e. , the limited coronary reserve. The ratio was lower in HCM and HT group than the control (p<0.001 and p<0.01). Patients with redistribution (subgroup A) in HCM showed a significantly lower ratio than the rest (subgroup B) (p<0.001), In group A, however, no difference in the ratio was observed between the areas with or without redistribution. The patients with cardiac hypertrophy have therefore a limited increase in coronary flow, i. e. , a limited coronary reserve. The existence of redistribution in Tl-scintigraphy is not the sole factor for the limited reserve. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 102, 号 1, p. 38-47, 発行日 1988-01 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
