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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第102巻第1号

Dipyridamole 負荷による, 肥大型心筋症及び高血圧性肥大心の冠血管予備能の検討 : ^<201>Tl 2回投与法を用いて

http://hdl.handle.net/10191/40585
http://hdl.handle.net/10191/40585
231ca05c-b00f-49df-9a71-6f0c4184ee66
名前 / ファイル ライセンス アクション
102(1)_38-47.pdf 102(1)_38-47.pdf (2.2 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-04-04
タイトル
タイトル Dipyridamole 負荷による, 肥大型心筋症及び高血圧性肥大心の冠血管予備能の検討 : ^<201>Tl 2回投与法を用いて
タイトル
言語 en
タイトル Dipyridamole 負荷による, 肥大型心筋症及び高血圧性肥大心の冠血管予備能の検討 : ^<201>Tl 2回投与法を用いて
言語
言語 jpn
キーワード
主題Scheme Other
主題 Dipyridamole
キーワード
主題Scheme Other
主題 coronary reserve
キーワード
主題Scheme Other
主題 reactive hyperemia
キーワード
主題Scheme Other
主題 Hypertrophic cardiomyopathy
キーワード
主題Scheme Other
主題 hypertensive heart disease
キーワード
主題Scheme Other
主題 Thallium-scintigraphy
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Assessment of the coronary reserve by dipyridamole loading : An experimental and clinical study
著者 里方, 美智子

× 里方, 美智子

WEKO 142075

里方, 美智子

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著者別名
識別子 142076
識別子Scheme WEKO
姓名 Satokata, Michiko
抄録
内容記述タイプ Abstract
内容記述 In order to study the coronary reserve by dipyridamole loading, we compared the maximal flow induced by dipyridamole with the post-occlusion reactive hyperemia in the closed-chest dog. The coronary flow increased gradually by systemic administration of dipyridamole(0.5mg/kg)and reached to 97% of the peak reactive hyperemic flow at 5 minutes after the administration. Intracoronary nitroglycerin little affected the coronary flow at the time of the maximal flow. Dipyridamole loading can therefore induce a sustaining maximal flow and abnormal lesions in the large vessel or the microcirculation will be detected as the limited maximal flow following dipyridamole. In patients with cardiomyopathy (HCM) or hypertension (HT), the coronary reserve was assessed from the ratio of thallium (Tl) uptake in the two-successive administration method. The low value of the ratio was supposed to reflect a limited increase of coronary flow, i. e. , the limited coronary reserve. The ratio was lower in HCM and HT group than the control (p<0.001 and p<0.01). Patients with redistribution (subgroup A) in HCM showed a significantly lower ratio than the rest (subgroup B) (p<0.001), In group A, however, no difference in the ratio was observed between the areas with or without redistribution. The patients with cardiac hypertrophy have therefore a limited increase in coronary flow, i. e. , a limited coronary reserve. The existence of redistribution in Tl-scintigraphy is not the sole factor for the limited reserve.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 102, 号 1, p. 38-47, 発行日 1988-01
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
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