WEKO3
アイテム
小児腎疾患における溶連菌成分に対する免疫応答性の免疫遺伝学的解析 : 第1報
http://hdl.handle.net/10191/41333
http://hdl.handle.net/10191/41333a3887b5c-29ea-4f6b-a74f-0007be6d46be
名前 / ファイル | ライセンス | アクション |
---|---|---|
![]() |
|
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2016-04-11 | |||||
タイトル | ||||||
タイトル | 小児腎疾患における溶連菌成分に対する免疫応答性の免疫遺伝学的解析 : 第1報 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 小児腎疾患における溶連菌成分に対する免疫応答性の免疫遺伝学的解析 : 第1報 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | streptococcal antigen | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | lymphocyte transformation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HLA | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 溶連菌成分 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | リンパ球芽球化反応 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Immune Responsiveness to Streptococcal Antigen in Children with Renal Disease : First Report | |||||
著者 |
佐藤, 敬以子
× 佐藤, 敬以子 |
|||||
著者別名 | ||||||
識別子 | 138191 | |||||
識別子Scheme | WEKO | |||||
姓名 | Satoh, Keiko | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Recent experience indicates that familial occurrence of renal disease is considerably more common than has been recognized hitherto. At the same time, it has been suggested that susceptibility to develop poststreptococcal acute glomerulonephritis (PSAGN) may be a familial trait. Association between PSAGN and HLA specificities has been demonstrated. Immune responsiveness to streptococcal antigen may thus play a role in the pathological process of a majority of patients with progressive glomerulonephritis. The purpose of this study was to investigate the immune responsiveness to streptococcal antigen in patients with renal disease. Families of index patients with hematuria, who was found by mass urine screening of school children, were studied. As a result of blocking experiments carried out with the addition of various antibodies, the immune response of peripheral blood lymphocytes to SLO was revealed to be menocyte-dependent T cell proliferation. Immune responsiveness to SLO was measured in families with familial hematuria detected by mass urine screening of school children. The intensity of the immune response was divided into two groups. Family study indicated that high response to SLO was a dominant trait. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 103, 号 7, p. 578-585, 発行日 1989-07 |
|||||
出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |