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夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析
http://hdl.handle.net/10191/41334
http://hdl.handle.net/10191/413349b57ecf5-5f1d-4429-9873-df02c789af5c
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
103(7)_549-555.pdf (1.5 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-04-11 | |||||
| タイトル | ||||||
| タイトル | 夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析 | |||||
| タイトル | ||||||
| タイトル | 夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | trophoblast | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | blocking antibodies | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | mixed lymphocyte reaction | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 絨毛細胞 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 遮断抗体 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | リンパ球混合培養 | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Studies on the Antigens Expressed on Trophoblasts Related to MLR-blocking Antibodies | |||||
| 著者 |
後藤, 重則
× 後藤, 重則 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 138183 | |||||
| 姓名 | Goto, Shigenori | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The purpose of this study is to investigate the antigenic nature of trophoblasts and its relation to mixed lymphocyte reaction-blocking antibodies (MLR-BAbs). Mixed culture of lymphocytes and syncytiotrophoblasts plasma membrane (STPM) (MLSC) and absorption study of MLR-blocking effect with STPM were perfomed in the present experiments. Lymphocytes were obviously stimulated in the 9 MLSCs. And like MLR, this stimulation was specifically inhibited by corresponding mothers' sera, suggesting that lymphocytes were stimulated in MLSCs by alloantigens expressed on STPM. Nineteen sera were obtained from normal pregnant women and habitual aborters after immunotherapy. And these sera were absorbed with STPM from respective mothers' placenta (autologous STPM) and unrelated mothers' (allogeneic STPM) as a control. The HLA types of cord blood lymphocytes corresponding to these STPM were then determined. The MLR-blocking effect of every serum was removed by autologous STPM absorption, nevertheless it was removed or unaffected by allogeneic one. Comparison of paternal stimulator and cord blood lymphocytes HLA-PR types showed that some of positive absorptions with allogeneic STPM could be explained by coincidence of HLA-DR types. These findings suggested that MLR-BAbs were directed against some alloantigens expressed on trophoblasts that might be related to HLA-DR antigens. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 103, 号 7, p. 549-555, 発行日 1989-07 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
