{"_buckets": {"deposit": "d1f3fff4-c99e-4a06-b818-1915d7794601"}, "_deposit": {"id": "22839", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22839"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022839"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Studies on the Antigens Expressed on Trophoblasts Related to MLR-blocking Antibodies"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-07", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "7", "bibliographicPageEnd": "555", "bibliographicPageStart": "549", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "The purpose of this study is to investigate the antigenic nature of trophoblasts and its relation to mixed lymphocyte reaction-blocking antibodies (MLR-BAbs). Mixed culture of lymphocytes and syncytiotrophoblasts plasma membrane (STPM) (MLSC) and absorption study of MLR-blocking effect with STPM were perfomed in the present experiments. Lymphocytes were obviously stimulated in the 9 MLSCs. And like MLR, this stimulation was specifically inhibited by corresponding mothers\u0027 sera, suggesting that lymphocytes were stimulated in MLSCs by alloantigens expressed on STPM. Nineteen sera were obtained from normal pregnant women and habitual aborters after immunotherapy. And these sera were absorbed with STPM from respective mothers\u0027 placenta (autologous STPM) and unrelated mothers\u0027 (allogeneic STPM) as a control. The HLA types of cord blood lymphocytes corresponding to these STPM were then determined. The MLR-blocking effect of every serum was removed by autologous STPM absorption, nevertheless it was removed or unaffected by allogeneic one. Comparison of paternal stimulator and cord blood lymphocytes HLA-PR types showed that some of positive absorptions with allogeneic STPM could be explained by coincidence of HLA-DR types. These findings suggested that MLR-BAbs were directed against some alloantigens expressed on trophoblasts that might be related to HLA-DR antigens.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "138183", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Goto, Shigenori"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u5f8c\u85e4, \u91cd\u5247"}], "nameIdentifiers": [{"nameIdentifier": "138182", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "103(7)_549-555.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1500000.0, "url": {"label": "103(7)_549-555.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22839/files/103(7)_549-555.pdf"}, "version_id": "69db8e92-077a-4bf5-aeda-7c248d1ce84f"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "trophoblast", "subitem_subject_scheme": "Other"}, {"subitem_subject": "blocking antibodies", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mixed lymphocyte reaction", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u7d68\u6bdb\u7d30\u80de", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u906e\u65ad\u6297\u4f53", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30ea\u30f3\u30d1\u7403\u6df7\u5408\u57f9\u990a", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "\u592b\u5a66\u9593\u30ea\u30f3\u30d1\u7403\u6df7\u5408\u57f9\u990a\u906e\u65ad\u6297\u4f53\u306b\u5bfe\u5fdc\u3059\u308b\u7d68\u6bdb\u7d30\u80de\u819c\u6297\u539f\u306e\u89e3\u6790", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "\u592b\u5a66\u9593\u30ea\u30f3\u30d1\u7403\u6df7\u5408\u57f9\u990a\u906e\u65ad\u6297\u4f53\u306b\u5bfe\u5fdc\u3059\u308b\u7d68\u6bdb\u7d30\u80de\u819c\u6297\u539f\u306e\u89e3\u6790"}, {"subitem_title": "\u592b\u5a66\u9593\u30ea\u30f3\u30d1\u7403\u6df7\u5408\u57f9\u990a\u906e\u65ad\u6297\u4f53\u306b\u5bfe\u5fdc\u3059\u308b\u7d68\u6bdb\u7d30\u80de\u819c\u6297\u539f\u306e\u89e3\u6790", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1208"], "permalink_uri": "http://hdl.handle.net/10191/41334", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-04-11"}, "publish_date": "2016-04-11", "publish_status": "0", "recid": "22839", "relation": {}, "relation_version_is_last": true, "title": ["\u592b\u5a66\u9593\u30ea\u30f3\u30d1\u7403\u6df7\u5408\u57f9\u990a\u906e\u65ad\u6297\u4f53\u306b\u5bfe\u5fdc\u3059\u308b\u7d68\u6bdb\u7d30\u80de\u819c\u6297\u539f\u306e\u89e3\u6790"], "weko_shared_id": null}