{"created":"2021-03-01T06:28:02.128912+00:00","id":22839,"links":{},"metadata":{"_buckets":{"deposit":"d1f3fff4-c99e-4a06-b818-1915d7794601"},"_deposit":{"id":"22839","owners":[],"pid":{"revision_id":0,"type":"depid","value":"22839"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00022839","sets":["453:456","471:537:538:1208"]},"item_7_alternative_title_1":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Studies on the Antigens Expressed on Trophoblasts Related to MLR-blocking Antibodies"}]},"item_7_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1989-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"555","bibliographicPageStart":"549","bibliographicVolumeNumber":"103","bibliographic_titles":[{"bibliographic_title":"新潟医学会雑誌"},{"bibliographic_title":"新潟医学会雑誌","bibliographic_titleLang":"en"}]}]},"item_7_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The purpose of this study is to investigate the antigenic nature of trophoblasts and its relation to mixed lymphocyte reaction-blocking antibodies (MLR-BAbs). Mixed culture of lymphocytes and syncytiotrophoblasts plasma membrane (STPM) (MLSC) and absorption study of MLR-blocking effect with STPM were perfomed in the present experiments. Lymphocytes were obviously stimulated in the 9 MLSCs. And like MLR, this stimulation was specifically inhibited by corresponding mothers' sera, suggesting that lymphocytes were stimulated in MLSCs by alloantigens expressed on STPM. Nineteen sera were obtained from normal pregnant women and habitual aborters after immunotherapy. And these sera were absorbed with STPM from respective mothers' placenta (autologous STPM) and unrelated mothers' (allogeneic STPM) as a control. The HLA types of cord blood lymphocytes corresponding to these STPM were then determined. The MLR-blocking effect of every serum was removed by autologous STPM absorption, nevertheless it was removed or unaffected by allogeneic one. Comparison of paternal stimulator and cord blood lymphocytes HLA-PR types showed that some of positive absorptions with allogeneic STPM could be explained by coincidence of HLA-DR types. These findings suggested that MLR-BAbs were directed against some alloantigens expressed on trophoblasts that might be related to HLA-DR antigens.","subitem_description_type":"Abstract"}]},"item_7_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"138183","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Goto, Shigenori"}]}]},"item_7_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"新潟医学会"}]},"item_7_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"publisher"}]},"item_7_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00182415","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00290440","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"後藤, 重則"}],"nameIdentifiers":[{"nameIdentifier":"138182","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-19"}],"displaytype":"detail","filename":"103(7)_549-555.pdf","filesize":[{"value":"1.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"103(7)_549-555.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/22839/files/103(7)_549-555.pdf"},"version_id":"69db8e92-077a-4bf5-aeda-7c248d1ce84f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"trophoblast","subitem_subject_scheme":"Other"},{"subitem_subject":"blocking antibodies","subitem_subject_scheme":"Other"},{"subitem_subject":"mixed lymphocyte reaction","subitem_subject_scheme":"Other"},{"subitem_subject":"絨毛細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"遮断抗体","subitem_subject_scheme":"Other"},{"subitem_subject":"リンパ球混合培養","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析"},{"subitem_title":"夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析","subitem_title_language":"en"}]},"item_type_id":"7","owner":"1","path":["456","1208"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-04-11"},"publish_date":"2016-04-11","publish_status":"0","recid":"22839","relation_version_is_last":true,"title":["夫婦間リンパ球混合培養遮断抗体に対応する絨毛細胞膜抗原の解析"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:53:07.681729+00:00"}