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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第103巻第8号

性ホルモンによる脳の性分化

http://hdl.handle.net/10191/41375
http://hdl.handle.net/10191/41375
bdefeb8d-fe8b-4150-b076-5caff9ed74c3
名前 / ファイル ライセンス アクション
103(8)_625-631.pdf 103(8)_625-631.pdf (1.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-04-12
タイトル
タイトル 性ホルモンによる脳の性分化
タイトル
言語 en
タイトル 性ホルモンによる脳の性分化
言語
言語 jpn
キーワード
主題Scheme Other
主題 sexual dimorphism
キーワード
主題Scheme Other
主題 lordosis
キーワード
主題Scheme Other
主題 brain development
キーワード
主題Scheme Other
主題 性行動
キーワード
主題Scheme Other
主題 脳の雌雄差
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Sexual Differentiation of the Brain
著者 佐久間, 康夫

× 佐久間, 康夫

WEKO 138096

佐久間, 康夫

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著者別名
識別子 138097
識別子Scheme WEKO
姓名 Sakuma, Yasuo
抄録
内容記述タイプ Abstract
内容記述 Lesion and electrical stimulation studies suggested antagonistic effects between the ventromedial hypothalamic nucleus (VMN) and the medial preoptic area (POA) on the control of lordosis, a sex-specific, estrogen-dependent component of female reproductive behavior in the rat. VMN cells with axons to the midbrain central gray (CG) have been demonstrated as a neural substrate for estrogen-induced facilitation of lordosis. Indeed, the excitability of these VMN cells in the ovariectomized females and neonatally castrated males increased following estrogen treatment, along with the behavioral activation. At the same time, marked suppression of the POA cells with projections to either the CG or ventral tegmental area was induced. Estrogen had no effect on the excitability of these neurons in the VMN and POA in the males castrated as adults or in the neonatally testosterone-treated females. In these animals, behavioral responses to estrogen was also absent. Mechanisms of the desensitization of the developing rat brain by sex steroids, which lead to the sexual dimorphism in the adult brain, are discussed.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 103, 号 8, p. 625-631, 発行日 1989-08
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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