{"_buckets": {"deposit": "4e4b974c-a7d0-4af1-a869-9220bfa13497"}, "_deposit": {"id": "22676", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22676"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022676", "sets": ["456", "1203"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "A Novel Experimental Model of Autoimmune Myocarditis(Autoimmune Diseases)"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "977", "bibliographicPageStart": "972", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Acute myocarditis has been suspected that its pathogenesis may be related to autoimmunity in part. Some of the experimental myocarditis by coxsakievirus B-3 were revealed that postinfection autoimmunity was an important mechanism of the diseases. Thus, we tried to establish an animal model of autoimmune myocarditis. Severe acute myocarditis can be induced in Lewis rats by immunization with human cardiac myosin in complete Freund\u0027s adjuvant. This myocarditis was characterized by massive pericardial effusion, marked enlargement of the heart, yellowish-white discoloration of the cardiac surface. In the lesion, remarkable cell infiltration containing multinucleated giant cells and extensive myocardial necrosis were observed. It was also found that the same lesion could be inducible in naive rats by the adoptive transfer of in vitro activated spleen cells from previously immunized rats. In conclusion, this experimental myocarditis is a cell mediated autoimmune disease and may provide a unique animal model to elucidate a pathogenesis of human myocarditis.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "137497", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kodama, Makoto"}]}, {"nameIdentifiers": [{"nameIdentifier": "137498", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Izumi, Tohru"}]}, {"nameIdentifiers": [{"nameIdentifier": "137499", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Shibata, Akira"}]}, {"nameIdentifiers": [{"nameIdentifier": "137500", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Matsumoto, Yoh"}]}, {"nameIdentifiers": [{"nameIdentifier": "137501", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Fujiwara, Michio"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "小玉, 誠"}], "nameIdentifiers": [{"nameIdentifier": "137492", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "和泉, 徹"}], "nameIdentifiers": [{"nameIdentifier": "137493", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "柴田, 昭"}], "nameIdentifiers": [{"nameIdentifier": "137494", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "松本, 陽"}], "nameIdentifiers": [{"nameIdentifier": "137495", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "藤原, 道夫"}], "nameIdentifiers": [{"nameIdentifier": "137496", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "103(12)_972-977.pdf", "filesize": [{"value": "2.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2500000.0, "url": {"label": "103(12)_972-977.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22676/files/103(12)_972-977.pdf"}, "version_id": "067d5e42-66d7-448d-b4de-0a72021ec244"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Autoimmune myocarditis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Giant cell myocarditis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cardiac myosin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Adoptive transfer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "自己免疫性心筋炎", "subitem_subject_scheme": "Other"}, {"subitem_subject": "巨細胞性心筋炎", "subitem_subject_scheme": "Other"}, {"subitem_subject": "心筋ミオシン", "subitem_subject_scheme": "Other"}, {"subitem_subject": "受身移入", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "3) 自己免疫性心筋炎 : 新しい動物モデルの確立(シンポジウム 自己免疫疾患, 第445回新潟医学会)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "3) 自己免疫性心筋炎 : 新しい動物モデルの確立(シンポジウム 自己免疫疾患, 第445回新潟医学会)"}, {"subitem_title": "3) 自己免疫性心筋炎 : 新しい動物モデルの確立(シンポジウム 自己免疫疾患, 第445回新潟医学会)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1203"], "permalink_uri": "http://hdl.handle.net/10191/41467", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-04-13"}, "publish_date": "2016-04-13", "publish_status": "0", "recid": "22676", "relation": {}, "relation_version_is_last": true, "title": ["3) 自己免疫性心筋炎 : 新しい動物モデルの確立(シンポジウム 自己免疫疾患, 第445回新潟医学会)"], "weko_shared_id": null}