{"_buckets": {"deposit": "112247d5-bbf0-4c96-a5cf-149ecadf40eb"}, "_deposit": {"id": "22674", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22674"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022674", "sets": ["456", "1203"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Autoantibodies in Systemic Lupus Erythematosus : Anti-DNA Antibody and Antiphospholipid Antibodies(Autoimmune Diseases)"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "967", "bibliographicPageStart": "961", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Systemic lupus erythematosus (SLE) is characterized by production of many autoantibodies. The clinical significance of the autoantibodies, especially anti-DNA antibody and antiphospholipid antibodies, was discussed in this paper. Anti-dsDNA antibody is highly specific for SLE and rarely seen in a significant titer in other rheumatic diseases. This antibody is useful for assessing desease activity. It can bind to several cellular components or bacterial polysaccharides, which suggest that the restricted anti-DNA antibody may account for the serological abnormalities and the tissue injury in SLE. Anti-phospholipid antibodies include BFP-STS, lupus anticoagulant, anti-cardiolipin antibody and anti-phosphatidyl serine antibody. These antibodies had a significant correlation with fetal wastage, thrombocytopenia, CNS lupus and thrombosis. We observed 3 patients who had successful pregnancies after anti-phosphatidyl serine antibody reduced to normal level. Anti-phpsphatidyl serine antibody is surely useful for the management of pregnancy in lupus patients.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "137483", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kikuchi, Masatoshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "137484", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ozawa, Tetsuo"}]}, {"nameIdentifiers": [{"nameIdentifier": "137485", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Satoh, Takehiro"}]}, {"nameIdentifiers": [{"nameIdentifier": "137486", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nakano, Masaaki"}]}, {"nameIdentifiers": [{"nameIdentifier": "137487", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Arakawa, Masaaki"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "菊池, 正俊"}], "nameIdentifiers": [{"nameIdentifier": "137478", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "小澤, 哲夫"}], "nameIdentifiers": [{"nameIdentifier": "137479", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "佐藤, 健比呂"}], "nameIdentifiers": [{"nameIdentifier": "137480", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "中野, 正明"}], "nameIdentifiers": [{"nameIdentifier": "137481", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "荒川, 正昭"}], "nameIdentifiers": [{"nameIdentifier": "137482", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-19"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "103(12)_961-967.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1500000.0, "url": {"label": "103(12)_961-967.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22674/files/103(12)_961-967.pdf"}, "version_id": "7f6f0b81-d044-4a04-9301-1656d7118349"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "SLE", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-DNA antibody", "subitem_subject_scheme": "Other"}, {"subitem_subject": "anti-phospholipid antibodies", "subitem_subject_scheme": "Other"}, {"subitem_subject": "全身性エリテマトーデス", "subitem_subject_scheme": "Other"}, {"subitem_subject": "抗DNA抗体", "subitem_subject_scheme": "Other"}, {"subitem_subject": "抗リン脂質抗体", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "1) 全身性エリテマトーデスにおける自己抗体の臨床意義 : とくに抗DNA抗体と抗リン脂質抗体について(シンポジウム 自己免疫疾患, 第445回新潟医学会)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "1) 全身性エリテマトーデスにおける自己抗体の臨床意義 : とくに抗DNA抗体と抗リン脂質抗体について(シンポジウム 自己免疫疾患, 第445回新潟医学会)"}, {"subitem_title": "1) 全身性エリテマトーデスにおける自己抗体の臨床意義 : とくに抗DNA抗体と抗リン脂質抗体について(シンポジウム 自己免疫疾患, 第445回新潟医学会)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1203"], "permalink_uri": "http://hdl.handle.net/10191/41471", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-04-13"}, "publish_date": "2016-04-13", "publish_status": "0", "recid": "22674", "relation": {}, "relation_version_is_last": true, "title": ["1) 全身性エリテマトーデスにおける自己抗体の臨床意義 : とくに抗DNA抗体と抗リン脂質抗体について(シンポジウム 自己免疫疾患, 第445回新潟医学会)"], "weko_shared_id": null}