{"_buckets": {"deposit": "112247d5-bbf0-4c96-a5cf-149ecadf40eb"}, "_deposit": {"id": "22674", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22674"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022674"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Autoantibodies in Systemic Lupus Erythematosus : Anti-DNA Antibody and Antiphospholipid Antibodies(Autoimmune Diseases)"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "967", "bibliographicPageStart": "961", "bibliographicVolumeNumber": "103", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Systemic lupus erythematosus (SLE) is characterized by production of many autoantibodies. The clinical significance of the autoantibodies, especially anti-DNA antibody and antiphospholipid antibodies, was discussed in this paper. Anti-dsDNA antibody is highly specific for SLE and rarely seen in a significant titer in other rheumatic diseases. This antibody is useful for assessing desease activity. It can bind to several cellular components or bacterial polysaccharides, which suggest that the restricted anti-DNA antibody may account for the serological abnormalities and the tissue injury in SLE. Anti-phospholipid antibodies include BFP-STS, lupus anticoagulant, anti-cardiolipin antibody and anti-phosphatidyl serine antibody. These antibodies had a significant correlation with fetal wastage, thrombocytopenia, CNS lupus and thrombosis. We observed 3 patients who had successful pregnancies after anti-phosphatidyl serine antibody reduced to normal level. Anti-phpsphatidyl serine antibody is surely useful for the management of pregnancy in lupus patients.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "137483", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kikuchi, Masatoshi"}]}, {"nameIdentifiers": [{"nameIdentifier": "137484", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ozawa, Tetsuo"}]}, {"nameIdentifiers": [{"nameIdentifier": "137485", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Satoh, Takehiro"}]}, {"nameIdentifiers": [{"nameIdentifier": "137486", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nakano, Masaaki"}]}, {"nameIdentifiers": [{"nameIdentifier": "137487", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Arakawa, Masaaki"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": 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