{"_buckets": {"deposit": "3589e34f-ef98-4476-98f3-6eec346b1568"}, "_deposit": {"id": "22187", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "22187"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00022187", "sets": ["456", "1197"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Selective Localization of Insulin-like Growth factor (IGF)-II Immunoreactivity in human tissues and in vitro activity of IGF-II"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1990-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "6", "bibliographicPageEnd": "453", "bibliographicPageStart": "447", "bibliographicVolumeNumber": "104", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Insulin-like growth factor (IGF)-II immunoreactivity in human tissues was detected with use of monoclonal antibody against rat IGF-II, which crossreacts to human IGF-II. The results indicated that IGF-II immunoreactivity localized selectively in normal paraganglionic cells including carotid body, adrenal medulla and retroperitoneal paraganglion. In addition, fetal kidney of 14th gestational week revealed IGF-II immunoreactivity in limited proximal convolution to its beginning segment. Other tissues were regularly negative for the immunoreactivity. All of 29 tumors originated from this paraganglionic system harbored IGF-II immunoreactive tumor cells with high frequency, although one tumor of glomus jugulare in origin failed to immunolabelling. IGF-II induced morphological differentiation of rat pheochromocytoma cell line PC 12 and also enhanced cell growth of human neuroblastoma cell line NB-45-nu F in vitro, as potent as nerve growth factor which caused same effects on these two cell lines. From these results, IGF-II might be a kind of nerve growth factor of human paraganglionic system.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "134884", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Suzuki, Toshimitsu"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "鈴木, 利光"}], "nameIdentifiers": [{"nameIdentifier": "134883", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "104(6)_447-453.pdf", "filesize": [{"value": "2.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 2500000.0, "url": {"label": "104(6)_447-453.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/22187/files/104(6)_447-453.pdf"}, "version_id": "67befcb1-9e2e-4715-ae42-9fe40e203492"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "IGF-II", "subitem_subject_scheme": "Other"}, {"subitem_subject": "paraganglionic cell", "subitem_subject_scheme": "Other"}, {"subitem_subject": "paraganglioma", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nerve growth factor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "インスリン様増殖因子-II", "subitem_subject_scheme": "Other"}, {"subitem_subject": "旁神経節", "subitem_subject_scheme": "Other"}, {"subitem_subject": "旁神経節腫", "subitem_subject_scheme": "Other"}, {"subitem_subject": "神経成長因子", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "インスリン様増殖因子(IGF)-IIの組織分布の特異性とそのin vitro活性", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "インスリン様増殖因子(IGF)-IIの組織分布の特異性とそのin vitro活性"}, {"subitem_title": "インスリン様増殖因子(IGF)-IIの組織分布の特異性とそのin vitro活性", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1197"], "permalink_uri": "http://hdl.handle.net/10191/34208", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-11-11"}, "publish_date": "2015-11-11", "publish_status": "0", "recid": "22187", "relation": {}, "relation_version_is_last": true, "title": ["インスリン様増殖因子(IGF)-IIの組織分布の特異性とそのin vitro活性"], "weko_shared_id": null}