WEKO3
アイテム
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円形脱毛症における組織内浸潤細胞の解析
http://hdl.handle.net/10191/35157
http://hdl.handle.net/10191/351575467f0b5-e579-4ffd-9779-78e9fd3f8b8f
名前 / ファイル | ライセンス | アクション |
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104(12)_1006-1012.pdf (2.5 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-12-08 | |||||
タイトル | ||||||
タイトル | 円形脱毛症における組織内浸潤細胞の解析 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 円形脱毛症における組織内浸潤細胞の解析 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | alopecia areata | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD4^+ cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD8^+ cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | monoclonal antibody | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Langerhans cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 円形脱毛症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD4^+細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD8^+細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | モノクローナル抗体 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ランゲルハンス細胞 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Immunohistochemical Analysis of the Cellular Infiltrate in Alopecia Areata | |||||
著者 |
松原, 三希子
× 松原, 三希子 |
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著者別名 | ||||||
識別子 | 132527 | |||||
識別子Scheme | WEKO | |||||
姓名 | Matsuhara, Mikiko | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The cellular infiltrates and the distributions of CD1-positive cells in the scalp skin lesions of 23 patients with alopecia areata were examined by immunoperoxidase method using monoclonal antibodies. In all the forms of alopecia areata, including common form, totalis, and universalis, the affected anagen hair apparatuses showed the cellular infiltrates frequently in the hair bulbs, the upper portions of hair follicles, and the surrounding perivascular area. Most of the infiltrating cells reacted with both CD3 and OKIal antibodies. CD4-positive cells always predominated over CD8-positive cells in all the anagen hair apparatus examined. The CD4/CD8 ratios were lower in the hair bulbs than those in the other portions. CD1-positive dendritic cells were distributed in the hair bulbs, the upper portions of the hair follicles, and epidermis. These findings suggest that the increased number of CD1-positive cells (Langerhans cells) in the anagen hair apparatus may be a primary event in the immune response and their anagen hair bulb may become a target for CD8-positive cells, resulting in shedding of the hair. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 104, 号 12, p. 1006-1012, 発行日 1990-12 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |