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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第105巻第3号

筋萎縮性側索硬化症における脊髄神経細胞脱落の特徴

http://hdl.handle.net/10191/38653
http://hdl.handle.net/10191/38653
aec72d07-1950-4352-8b3f-290d57a25b78
名前 / ファイル ライセンス アクション
105(3)_147-154.pdf 105(3)_147-154.pdf (1.0 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-22
タイトル
タイトル 筋萎縮性側索硬化症における脊髄神経細胞脱落の特徴
タイトル
言語 en
タイトル 筋萎縮性側索硬化症における脊髄神経細胞脱落の特徴
言語
言語 jpn
キーワード
主題Scheme Other
主題 ALS
キーワード
主題Scheme Other
主題 spinal cord
キーワード
主題Scheme Other
主題 anterior horn cell
キーワード
主題Scheme Other
主題 intermediate zone
キーワード
主題Scheme Other
主題 morphometric study
キーワード
主題Scheme Other
主題 筋萎縮性側索硬化症
キーワード
主題Scheme Other
主題 脊髄
キーワード
主題Scheme Other
主題 前角細胞
キーワード
主題Scheme Other
主題 中間帯
キーワード
主題Scheme Other
主題 定量形態
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Topographic and Quantitative Investigation of the Spinal Neurons in Amyotrophic Lateral Sclerosis
著者 小柳, 清光

× 小柳, 清光

WEKO 131616

小柳, 清光

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著者別名
識別子 131617
識別子Scheme WEKO
姓名 Oyanagi, Kiyomitsu
抄録
内容記述タイプ Abstract
内容記述 In order to visualize the distribution of neurons in the normal human spinal cord and the topographical distribution of degenerative cells in patients with classical amyotrophic lateral sclerosis (ALS), an atlas of the localization of spinal neurons was prepared with special reference to nuclear sizes. Serial sections of spinal cord tissues from three ALS and three control cases were stained with thionine and the nuclear dimensions of the neurons in the entire gray matter at the cervical, thoracic, and sacral levels were measured. 1. In the spinal gray matter of the advanced ALS patients, there was a decrease in number of middle-sized neurons (nuclear area: 71~120μm^2) in Rexed's laminae VI, VII and VIII, possibly including the propriospinal tract neurons and interneurons, in addition to the complete loss of large neurons (nuclear area : greater than 151μm^2) in the anterior horn. The intermediolateral nucleus of the thoracic segment was also affected. There were no significant changes, however, in the neurons of the posterior horn or in the distribution of small neurons (nuclear area: 70μm^2 and less) throughout the spinal gray matter. 2. In the spinal cord of a patient with ALS, whose muscular strength was fairly well preserved up to death, the loss of anterior horn cells was severe but the degree was not equal to that of advanced ALS patients, and the neurons in the intermediate zone were quite well preserved. The finding indicates that the primary degeneration may occur in the anterior horn cells and the neurons in the intermediate zone degenerate sequentially in the spinal gray matter in ALS.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 105, 号 3, p. 147-154, 発行日 1991-03
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
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