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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第105巻第8号

NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用

http://hdl.handle.net/10191/39328
http://hdl.handle.net/10191/39328
b0ab5f86-c41c-4b4a-bb85-cadbe25c687e
名前 / ファイル ライセンス アクション
105(8)_520-527.pdf 105(8)_520-527.pdf (1.3 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-03-10
タイトル
タイトル NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用
タイトル
言語 en
タイトル NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用
言語
言語 jpn
キーワード
主題Scheme Other
主題 nitroglycerin
キーワード
主題Scheme Other
主題 nitric oxide
キーワード
主題Scheme Other
主題 methylene blue
キーワード
主題Scheme Other
主題 cGMP
キーワード
主題Scheme Other
主題 smooth muscle
キーワード
主題Scheme Other
主題 ニトログリセリン
キーワード
主題Scheme Other
主題 酸化窒素
キーワード
主題Scheme Other
主題 メチレンブルー
キーワード
主題Scheme Other
主題 平滑筋
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Relaxation of Vascular and Nonvascular Smooth Muscles by Nitroglycerin and Nitric Oxide and the Effects Thereupon of Methylene Blue
著者 付, 守廷

× 付, 守廷

WEKO 130351

付, 守廷

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著者別名
識別子 130352
識別子Scheme WEKO
姓名 Fu, Shou-Ting
抄録
内容記述タイプ Abstract
内容記述 Smooth muscle relaxant activity by nitroglycerin and nitric oxide was measured in the smooth muscle preparations of guinea pig aorta, trachea and taenia coli. The smooth muscle preparations were precontracted with either 100mM KCl, 30mM KCl or histamine. The relaxant potency of nitroglycerin in these smooth muscles was aorta>trachea>taenia coli. In contrast, the relaxant potency of nitric oxide was aorta>taenia coli>trachea. Methylene blue inhibited relaxation by both nitric oxide and nitroglycerin in the aorta precontracted by 100mM, 30mM K and 3×10^<-6>M histamine and in the trachea precontracted by 3×10^<-5>M histamine, but did not inhibit in the trachea precontracted by 100mM, 30mM K and in the taenia coli precontracted by 100mM, 30mM K and histamine. These results suggest that relaxation of vascular smooth muscle caused by nitric oxide and nitroglycerine is ultimately connected with the activation of soluble guanylate cyclase, but those of the trachea and taenia coli are not related with the activation of the enzyme.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 105, 号 8, p. 520-527, 発行日 1991-08
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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