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アイテム
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NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用
http://hdl.handle.net/10191/39328
http://hdl.handle.net/10191/39328b0ab5f86-c41c-4b4a-bb85-cadbe25c687e
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-03-10 | |||||
タイトル | ||||||
タイトル | NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | nitroglycerin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | nitric oxide | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | methylene blue | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cGMP | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | smooth muscle | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ニトログリセリン | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 酸化窒素 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | メチレンブルー | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 平滑筋 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Relaxation of Vascular and Nonvascular Smooth Muscles by Nitroglycerin and Nitric Oxide and the Effects Thereupon of Methylene Blue | |||||
著者 |
付, 守廷
× 付, 守廷 |
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著者別名 | ||||||
識別子 | 130352 | |||||
識別子Scheme | WEKO | |||||
姓名 | Fu, Shou-Ting | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Smooth muscle relaxant activity by nitroglycerin and nitric oxide was measured in the smooth muscle preparations of guinea pig aorta, trachea and taenia coli. The smooth muscle preparations were precontracted with either 100mM KCl, 30mM KCl or histamine. The relaxant potency of nitroglycerin in these smooth muscles was aorta>trachea>taenia coli. In contrast, the relaxant potency of nitric oxide was aorta>taenia coli>trachea. Methylene blue inhibited relaxation by both nitric oxide and nitroglycerin in the aorta precontracted by 100mM, 30mM K and 3×10^<-6>M histamine and in the trachea precontracted by 3×10^<-5>M histamine, but did not inhibit in the trachea precontracted by 100mM, 30mM K and in the taenia coli precontracted by 100mM, 30mM K and histamine. These results suggest that relaxation of vascular smooth muscle caused by nitric oxide and nitroglycerine is ultimately connected with the activation of soluble guanylate cyclase, but those of the trachea and taenia coli are not related with the activation of the enzyme. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 105, 号 8, p. 520-527, 発行日 1991-08 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |