{"_buckets": {"deposit": "49de83f2-3ff3-4765-8a86-da9f73ab82db"}, "_deposit": {"id": "21289", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "21289"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00021289"}, "item_7_alternative_title_1": {"attribute_name": "\u305d\u306e\u4ed6\u306e\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_alternative_title": "Relaxation of Vascular and Nonvascular Smooth Muscles by Nitroglycerin and Nitric Oxide and the Effects Thereupon of Methylene Blue"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "8", "bibliographicPageEnd": "527", "bibliographicPageStart": "520", "bibliographicVolumeNumber": "105", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c"}, {"bibliographic_title": "\u65b0\u6f5f\u533b\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Smooth muscle relaxant activity by nitroglycerin and nitric oxide was measured in the smooth muscle preparations of guinea pig aorta, trachea and taenia coli. The smooth muscle preparations were precontracted with either 100mM KCl, 30mM KCl or histamine. The relaxant potency of nitroglycerin in these smooth muscles was aorta\u003etrachea\u003etaenia coli. In contrast, the relaxant potency of nitric oxide was aorta\u003etaenia coli\u003etrachea. Methylene blue inhibited relaxation by both nitric oxide and nitroglycerin in the aorta precontracted by 100mM, 30mM K and 3\u00d710^\u003c-6\u003eM histamine and in the trachea precontracted by 3\u00d710^\u003c-5\u003eM histamine, but did not inhibit in the trachea precontracted by 100mM, 30mM K and in the taenia coli precontracted by 100mM, 30mM K and histamine. These results suggest that relaxation of vascular smooth muscle caused by nitric oxide and nitroglycerine is ultimately connected with the activation of soluble guanylate cyclase, but those of the trachea and taenia coli are not related with the activation of the enzyme.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "130352", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Fu, Shou-Ting"}]}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "\u65b0\u6f5f\u533b\u5b66\u4f1a"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u4ed8, \u5b88\u5ef7"}], "nameIdentifiers": [{"nameIdentifier": "130351", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "105(8)_520-527.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "105(8)_520-527.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/21289/files/105(8)_520-527.pdf"}, "version_id": "ba100634-d037-4018-b2bc-50ce2aad226c"}]}, "item_keyword": {"attribute_name": "\u30ad\u30fc\u30ef\u30fc\u30c9", "attribute_value_mlt": [{"subitem_subject": "nitroglycerin", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nitric oxide", "subitem_subject_scheme": "Other"}, {"subitem_subject": "methylene blue", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cGMP", "subitem_subject_scheme": "Other"}, {"subitem_subject": "smooth muscle", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30cb\u30c8\u30ed\u30b0\u30ea\u30bb\u30ea\u30f3", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u9178\u5316\u7a92\u7d20", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u30e1\u30c1\u30ec\u30f3\u30d6\u30eb\u30fc", "subitem_subject_scheme": "Other"}, {"subitem_subject": "\u5e73\u6ed1\u7b4b", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Nitroglycerin\u3068NO\u306b\u3088\u308b\u5e73\u6ed1\u7b4b\u5f1b\u7de9\u3068\u305d\u308c\u306b\u5bfe\u3059\u308bmethylene blue\u306e\u4f5c\u7528", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Nitroglycerin\u3068NO\u306b\u3088\u308b\u5e73\u6ed1\u7b4b\u5f1b\u7de9\u3068\u305d\u308c\u306b\u5bfe\u3059\u308bmethylene blue\u306e\u4f5c\u7528"}, {"subitem_title": "Nitroglycerin\u3068NO\u306b\u3088\u308b\u5e73\u6ed1\u7b4b\u5f1b\u7de9\u3068\u305d\u308c\u306b\u5bfe\u3059\u308bmethylene blue\u306e\u4f5c\u7528", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/538/1183"], "permalink_uri": "http://hdl.handle.net/10191/39328", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2016-03-10"}, "publish_date": "2016-03-10", "publish_status": "0", "recid": "21289", "relation": {}, "relation_version_is_last": true, "title": ["Nitroglycerin\u3068NO\u306b\u3088\u308b\u5e73\u6ed1\u7b4b\u5f1b\u7de9\u3068\u305d\u308c\u306b\u5bfe\u3059\u308bmethylene blue\u306e\u4f5c\u7528"], "weko_shared_id": null}