@article{oai:niigata-u.repo.nii.ac.jp:00021289,
 author = {付, 守廷},
 issue = {8},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Aug},
 note = {Smooth muscle relaxant activity by nitroglycerin and nitric oxide was measured in the smooth muscle preparations of guinea pig aorta, trachea and taenia coli. The smooth muscle preparations were precontracted with either 100mM KCl, 30mM KCl or histamine. The relaxant potency of nitroglycerin in these smooth muscles was aorta>trachea>taenia coli. In contrast, the relaxant potency of nitric oxide was aorta>taenia coli>trachea. Methylene blue inhibited relaxation by both nitric oxide and nitroglycerin in the aorta precontracted by 100mM, 30mM K and 3×10^<-6>M histamine and in the trachea precontracted by 3×10^<-5>M histamine, but did not inhibit in the trachea precontracted by 100mM, 30mM K and in the taenia coli precontracted by 100mM, 30mM K and histamine. These results suggest that relaxation of vascular smooth muscle caused by nitric oxide and nitroglycerine is ultimately connected with the activation of soluble guanylate cyclase, but those of the trachea and taenia coli are not related with the activation of the enzyme.},
 pages = {520--527},
 title = {NitroglycerinとNOによる平滑筋弛緩とそれに対するmethylene blueの作用},
 volume = {105},
 year = {1991}
}