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A 64-yers-old female (case 1) were found to have a markedly prolonged cloting time and aPTT in preoperative coagulation tests. The F.XII cloting activity was 9.2% and F.XII antigen was 2.5% (cross-reacting material negative). This case was thought about heterozygote. And in this case DDAVP was infused 10\u03bcg/body. The levels of F.VIII was increased and aPTT was reduced markedlly after infusion. And F.XII activity was slightly increased. A 49-yers-old female (case 2) were found by nasal bleeding and to have markedly prolonged clotingtime and aPTT. And the F.XII activity was less than 1%. We also reviewed 23 families of Hageman factor deficiency previousiy described in Japan.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "130325", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kurihara, Atushi"}]}, {"nameIdentifiers": [{"nameIdentifier": "130326", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Kobayashi, Iasao"}]}, {"nameIdentifiers": [{"nameIdentifier": "130327", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Hamaoka, Satomi"}]}, {"nameIdentifiers": [{"nameIdentifier": "130328", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Ozawa, Hideyuki"}]}, {"nameIdentifiers": [{"nameIdentifier": "130329", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Nakajima, Atuko"}]}, {"nameIdentifiers": [{"nameIdentifier": "130330", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Tamura, Kohji"}]}]}, "item_7_publisher_7": 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