@article{oai:niigata-u.repo.nii.ac.jp:00021284,
 author = {栗原, 淳 and 小林, 勲 and 浜岡, 里美 and 小沢, 秀行 and 中島, 淳子 and 田村, 康二},
 issue = {9},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Sep},
 note = {Tow cases with congenital F.XII deficiency from tow families were reported. A 64-yers-old female (case 1) were found to have a markedly prolonged cloting time and aPTT in preoperative coagulation tests. The F.XII cloting activity was 9.2% and F.XII antigen was 2.5% (cross-reacting material negative). This case was thought about heterozygote. And in this case DDAVP was infused 10μg/body. The levels of F.VIII was increased and aPTT was reduced markedlly after infusion. And F.XII activity was slightly increased. A 49-yers-old female (case 2) were found by nasal bleeding and to have markedly prolonged clotingtime and aPTT. And the F.XII activity was less than 1%. We also reviewed 23 families of Hageman factor deficiency previousiy described in Japan.},
 pages = {639--645},
 title = {6) 第XII因子欠乏症の2症例(新潟血栓止血研究会10周年記念特別例会記録)},
 volume = {105},
 year = {1991}
}