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新しい胃癌株, 胃内分泌細胞癌培養株, の樹立とその特性
http://hdl.handle.net/10191/39493
http://hdl.handle.net/10191/3949376ee6c18-9020-471d-80b8-62e43d523d67
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
106(01)_21-36.pdf (6.2 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-03-14 | |||||
| タイトル | ||||||
| タイトル | 新しい胃癌株, 胃内分泌細胞癌培養株, の樹立とその特性 | |||||
| タイトル | ||||||
| タイトル | 新しい胃癌株, 胃内分泌細胞癌培養株, の樹立とその特性 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | endocrine cell carcinoma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | cell line | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | gastric cancer | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | small cell carcinoma | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | immunohistochemistry | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 内分泌細胞癌 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 培養細胞株 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 胃癌 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 小細胞癌 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 免疫組織化学 | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Establishment and Characterization of New Gastric Carcinoma Cell Lines Derived from Endocrine Cell Carcinoma | |||||
| 著者 |
石原, 法子
× 石原, 法子 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 129830 | |||||
| 姓名 | Ishihara, Noriko | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | New cell lines (ECC10 and ECC12) derived from endocrine cell carcinoma (ECC) or small cell carcinoma (SCC) of the stomach were established and characterized. Primary tumor of ECC10 was an early carcinoma composed of ECC with squamous cell carcinoma (SQCC) and of well differentiated tubular adenocarcinoma, while that of ECC12 was an advanced carcinoma solely composed of ECC. Inoculation tumor of ECC10 was hepatic metastatic tumor with ECC and SQCC and that of ECC12 was skin metastatic tumor with ECC. ECC10 grew as both of adherent and floating aggregates and ECC12 grew as adherent aggregates. Both cell lines showed aneuploidy, about 46 hours of population doubling time, and successful xenotransplantation into athymic nude mice. ECC10 and ECC12 were composed of argyrophil cells with constant neurosecretory granules. Immunohistochemically ECC10 was negative for serotonin, peptide hormones, and chromogranin A. But, ECC12 contained some cells positive for serotonin, peptide YY, neuropeptide Y, and chromogranin A. Neuron specific enolase was positive in both cell lines, but carcinoembrionic antigen was negative. ECC10 and ECC12 still retain the characteristics of ECC components of their parent tumors and share many properties with classic type of pulmonary SCC cell lines. They are the first gastric ECC cell lines and can provide unique tools for elucidating the biological properties of gastric ECC. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 106, 号 1, p. 21-36, 発行日 1992-01 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
