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糖尿病ラットにおけるバナデートの腎への効果
http://hdl.handle.net/10191/37397
http://hdl.handle.net/10191/37397bf164a05-930e-4290-abe1-b9a8ed4aa209
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
107(5)_438-443.pdf (1.5 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2016-02-02 | |||||
| タイトル | ||||||
| タイトル | 糖尿病ラットにおけるバナデートの腎への効果 | |||||
| タイトル | ||||||
| タイトル | 糖尿病ラットにおけるバナデートの腎への効果 | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | streptozotocin diabetes | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | vanadate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | albumin excretion rate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | IgG excretion rate | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | renal hypertrophy | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | ストレプトゾトシン糖尿病 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | バナデート | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | アルブミン排泄率 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | IgG 排泄率 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | 腎肥大 | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| その他のタイトル | ||||||
| その他のタイトル | Effect of Vanadate on Renal Function in Streptozotocin-Induced Diabetic Rats | |||||
| 著者 |
中澤, 朝生
× 中澤, 朝生 |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 124705 | |||||
| 姓名 | Nakazawa, Asao | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Vanadate of a trace element has been shown to have insulin-like effects. The effect of vanadate on some parameters of renal function was studied on streptozotocin-induced diabetic rats with heminephrectomy. Rats were divided into four groups as follows: vanadate (v)-untreated normal rats, v-treated normal rats, v-untreated diabetic rats and v-treated diabetic rats. Oral administration of vanadate was started three weeks after the induction of diabetes and continued for a period of 10 weeks. The v-treated diabetic rats were characterized by significant (p<0.001) decreases of blood glucose and of both albumin and IgG excretion rates after 8 weeks of study. There was no significant difference in the blood glucose and both albumin and IgG excretion rates between v-untreated normal rats and v-treated normal rats. The kidney wet weights of the v-untreated diabetic rats were significantly (p<0.01) greater than those in the v-treated diabetic rats. However there was no significant difference in the body weight and creatinine clearance between the v-treated diabetic rats and the v-untreated diabetic rats. The present findings suggest that glycemic control by oral administration of vanadate, which dose not cause insulin release, also improves diabetic renal function. | |||||
| 書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 107, 号 5, p. 438-443, 発行日 1993-05 |
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| 出版者 | ||||||
| 出版者 | 新潟医学会 | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00290440 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AN00182415 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
