{"_buckets": {"deposit": "6397bb89-f0b3-4ef2-8ce1-967b81a5f5b0"}, "_deposit": {"id": "2000534", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2000534"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:02000534", "sets": []}, "author_link": [], "item_1627361970403": {"attribute_name": "\u51fa\u7248\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "57", "bibliographicPageStart": "51", "bibliographicVolumeNumber": "45", "bibliographic_titles": [{"bibliographic_title": "\u65b0\u6f5f\u6b6f\u5b66\u4f1a\u96d1\u8a8c", "bibliographic_titleLang": "ja"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "In recent years, the elderly population has been growing, and subsequently, the number of patients complaining of xerostomia symptoms has been increasing. In this study, we focused on the moisturizing effects of trehalose. We developed a trehalose tablet as a novel supplement for xerostomia and compared it to a sucrose tablet for verification of its moisturizing effects. A total of 72 healthy female subjects were randomly assigned to receive either the sucrose or trehalose tablet, followed by the other. Subjects received a 14-question survey soon after each tablet had dissolved completely in the mouth. For objective evaluation of the tablets, compression and solubility tests were performed. Based on sensory (subjective) evaluation, the trehalose tablets provided significantly more moisturization in the mouth and a sense of salivation than the sucrose tablets. Therefore, trehalose may confer a greater effect on moisturizing the mouth than sucrose. In addition, the trehalose tablets were about 2/3 as soft and dissolved 2 to 3 times more quickly than the sucrose tablets. These subjective and objective evaluations suggest that trehalose is a better supplement for maintaining oral moisture than sucrose, and may therefore be useful as a therapeutic supplement. The use of this convenient and safe therapeutic supplement could help improve the quality of life of elderly individuals who are suffering from xerostomia by allowing them to better enjoy meals and conversation.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}, {"subitem_description": 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