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糖尿病患者の透析導入期におけるswept-source 光干渉断層計を用いた脈絡膜構造評価
http://hdl.handle.net/10191/0002000299
http://hdl.handle.net/10191/0002000299bfb4393d-7e98-4c23-868b-398c6ac47edb
名前 / ファイル | ライセンス | アクション |
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本文 (0.99MB)
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要旨 (544KB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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公開日 | 2022-04-04 | |||||||||
タイトル | ||||||||||
言語 | en | |||||||||
タイトル | Choroid structure analysis following initiation of hemodialysis using swept-source optical coherence tomography in patients with and without diabetes | |||||||||
タイトル | ||||||||||
言語 | ja | |||||||||
タイトル | 糖尿病患者の透析導入期におけるswept-source 光干渉断層計を用いた脈絡膜構造評価 | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源 | http://purl.org/coar/resource_type/c_db06 | |||||||||
タイプ | doctoral thesis | |||||||||
アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
著者 |
中野, 英之
× 中野, 英之
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抄録 | ||||||||||
内容記述タイプ | Abstract | |||||||||
内容記述 | We aimed to evaluate choroid structural changes using swept-source optical coherence tomography (SS-OCT) following hemodialysis initiation in diabetic and nondiabetic patients with end-stage kidney disease (ESKD). In this multicenter, prospective, cross-sectional study, diabetic (DM group; 30 eyes; 16 patients) and nondiabetic patients (NDM group; 30 eyes; 15 patients) with ESKD were evaluated after hemodialysis initiation. SS-OCT findings were analyzed using a manual delineation technique and binarization method before the first and last hemodialysis sessions, conducted approximately 2 weeks apart. Subfoveal choroidal thickness changes and mean large choroidal vessel layer thickness were significantly greater in the DM group (−13.3%±2.5% and −14.5%±5.2%, respectively) than the NDM group (−9.5%±3.1% and −9.2%±3.4%, respectively; p = 0.049 and p = 0.02, respectively). Binarized SS-OCT analysis revealed that the mean subfoveal choroidal area was significantly larger in the DM group (−21.9%±6.5%) than the NDM group (−17.2%±5.9%; p = 0.032). The change ratio in mean luminal area values was significantly greater in the DM group (−27.7%±8.7%) than the NDM group (−17.7%±5.8%; p = 0.007). The DM group exhibited substantial changes in the choroidal layer, possibly reflecting choroidal vascular disorders caused by diabetes. | |||||||||
言語 | en | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | PLoS ONE. 2020, 15(9), e0239072. | |||||||||
言語 | en | |||||||||
DOI | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.1371/journal.pone.0239072 | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報 | 【○!C】 2020 Nakano et al. | |||||||||
権利 | ||||||||||
言語 | en | |||||||||
権利情報Resource | https://creativecommons.org/licenses/by/4.0/ | |||||||||
権利情報 | Creative Commons Attribution 4.0 International | |||||||||
学位名 | ||||||||||
言語 | ja | |||||||||
学位名 | 博士(医学) | |||||||||
学位授与機関 | ||||||||||
学位授与機関識別子Scheme | kakenhi | |||||||||
学位授与機関識別子 | 13101 | |||||||||
言語 | ja | |||||||||
学位授与機関名 | 新潟大学 | |||||||||
言語 | en | |||||||||
学位授与機関名 | Niigata University | |||||||||
学位授与年月日 | ||||||||||
学位授与年月日 | 2021-03-23 | |||||||||
学位授与番号 | ||||||||||
学位授与番号 | 甲第4840号 | |||||||||
学位記番号 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 新大院博(医)第994号 | |||||||||
言語 | ja |