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Changes in Glycolipid Metabolism During A High-Sucrose Feeding in Spontaneously Diabetic Torii (SDT) Rats, A Genetic Model of Nonobese Type 2 Diabetes
http://hdl.handle.net/10191/30615
http://hdl.handle.net/10191/30615f59afdd3-71b6-4fe3-91af-f0e158946087
名前 / ファイル | ライセンス | アクション |
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-12-01 | |||||
タイトル | ||||||
タイトル | Changes in Glycolipid Metabolism During A High-Sucrose Feeding in Spontaneously Diabetic Torii (SDT) Rats, A Genetic Model of Nonobese Type 2 Diabetes | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Changes in Glycolipid Metabolism During A High-Sucrose Feeding in Spontaneously Diabetic Torii (SDT) Rats, A Genetic Model of Nonobese Type 2 Diabetes | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Diabetes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | high-sucrose diet | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rat | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | abnormality | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fatty liver | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | serum | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | journal article | |||||
著者 |
Ohta, Takeshi
× Ohta, Takeshi× Miyajima, Katsuhiro× Yamada, Takahisa |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A high-sucrose diet induces insulin resistance and dyslipidemia in normal rats. The purpose of the present study was to investigate the effects of a high-sucrose diet on glycolipid metabolism in Spontaneously Diabetic Torii (SDT) rats, a genetic model of nonobese type 2 diabetes. Male SDT rats were fed with a high-sucrose (68% of energy) diet from 8-24 weeks of age. SDT rats fed a high-sucrose diet showed hypercholesterolemia, hyperinsulinemia and hyperleptinemia but the body weight and the serum triglyceride level were not increased. Unexpectedly in SDT rats fed a high-sucrose diet, we observed a suppress of the incidence of diabetes mellitus. In computed tomography analysis, SDT rats fed a high-sucrose diet showed an increase of visceral or subcutaneous fat tissue weight. In pathological analyses, slight or mild fatty liver was observed by high-sucrose feeding. A high-sucrose diet in SDT rats induced dyslipidemia, insulin resistance and fat storage but not development of diabetes. High sucrose-fed diabetic rats are considered to be useful for further elucidation of complex mechanisms in glycolipid metabolic abnormality. | |||||
書誌情報 |
Journal of animal and veterinary advances en : Journal of animal and veterinary advances 巻 9, 号 22, p. 2883-2889, 発行日 2010-12 |
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出版者 | ||||||
出版者 | Medwell Journals | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 16805593 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | info:doi/10.3923/javaa.2010.2883.2889 | |||||
権利 | ||||||
権利情報 | Copyright(C)2010 Medwell Journals | |||||
著者版フラグ | ||||||
値 | publisher | |||||
異版である | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | URI | |||||
関連識別子 | http://docsdrive.com/pdfs/medwelljournals/javaa/2010/2883-2889.pdf |