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腸上皮細胞の細胞死(アポトーシス)に関わるマクロファージと上皮内リンパ球
http://hdl.handle.net/10191/38107
http://hdl.handle.net/10191/381074f26ef74-d9e1-4763-af73-df8267dbb116
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-02-08 | |||||
タイトル | ||||||
タイトル | 腸上皮細胞の細胞死(アポトーシス)に関わるマクロファージと上皮内リンパ球 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 腸上皮細胞の細胞死(アポトーシス)に関わるマクロファージと上皮内リンパ球 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | enterocytes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | apoptosis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | macrophages | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | intraepithelial lymphocytes | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 腸上皮細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | アポトーシス | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | マクロファージ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 上皮内リンパ球 | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Macrophages and Intraepithelial Lymphocytes Involved in the Apoptosis of Intestinal Epithelial Cells | |||||
著者 |
岩永, 敏彦
× 岩永, 敏彦× 韓, 紅霞 |
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著者別名 | ||||||
識別子 | 121119 | |||||
識別子Scheme | WEKO | |||||
姓名 | Iwanaga, Toshihiko | |||||
著者別名 | ||||||
識別子 | 121120 | |||||
識別子Scheme | WEKO | |||||
姓名 | Han, Hongxia | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Numerous macrophages are aggregated at the villus tips in the small intestine of guinea pigs and monkeys. The macrophages are characterized by rich existence of large phagosomes which contain cellular elements. Morphological observation shows that effete enterocytes are not simply exfoliated into the lumen but phagocytosed by the subepithelial macrophages. The epithelium of the villus tips is infiltrated with numerous large granular lymphocytes. The cytotoxic lymphocytes with an intense perforin immunoreactivity are actively interdigitated with apoptotic enterocytes, suggesting the lymphocyte-mediated cell death. In the rat and mouse, no aggregation of phagocytotic macrophages is found in the lamina propria of villus tips. The enterocytes undergoing apoptosis are exfoliated as total, nucleus-containing cells into the lumen. Ultrastructural and cytochemical studies suggest that in the rat and mouse, lamina propria macrophages rather than intraepithelial lymphocytes are involved in cell death of enterocytes. In the human, the aggregation of macrophages is observed in the large intestine, especially the rectum. The intimate relationship between the lamina propria macrophages and the ulcerative colitis is shown experimentally and clinically. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 108, 号 3, p. 167-172, 発行日 1994-03 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |