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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第108巻第3号

腸上皮細胞の細胞死(アポトーシス)に関わるマクロファージと上皮内リンパ球

http://hdl.handle.net/10191/38107
http://hdl.handle.net/10191/38107
4f26ef74-d9e1-4763-af73-df8267dbb116
名前 / ファイル ライセンス アクション
108(3)_167-172.pdf 108(3)_167-172.pdf (2.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-08
タイトル
タイトル 腸上皮細胞の細胞死(アポトーシス)に関わるマクロファージと上皮内リンパ球
タイトル
言語 en
タイトル 腸上皮細胞の細胞死(アポトーシス)に関わるマクロファージと上皮内リンパ球
言語
言語 jpn
キーワード
主題Scheme Other
主題 enterocytes
キーワード
主題Scheme Other
主題 apoptosis
キーワード
主題Scheme Other
主題 macrophages
キーワード
主題Scheme Other
主題 intraepithelial lymphocytes
キーワード
主題Scheme Other
主題 腸上皮細胞
キーワード
主題Scheme Other
主題 アポトーシス
キーワード
主題Scheme Other
主題 マクロファージ
キーワード
主題Scheme Other
主題 上皮内リンパ球
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Macrophages and Intraepithelial Lymphocytes Involved in the Apoptosis of Intestinal Epithelial Cells
著者 岩永, 敏彦

× 岩永, 敏彦

WEKO 121117

岩永, 敏彦

Search repository
韓, 紅霞

× 韓, 紅霞

WEKO 121118

韓, 紅霞

Search repository
著者別名
識別子 121119
識別子Scheme WEKO
姓名 Iwanaga, Toshihiko
著者別名
識別子 121120
識別子Scheme WEKO
姓名 Han, Hongxia
抄録
内容記述タイプ Abstract
内容記述 Numerous macrophages are aggregated at the villus tips in the small intestine of guinea pigs and monkeys. The macrophages are characterized by rich existence of large phagosomes which contain cellular elements. Morphological observation shows that effete enterocytes are not simply exfoliated into the lumen but phagocytosed by the subepithelial macrophages. The epithelium of the villus tips is infiltrated with numerous large granular lymphocytes. The cytotoxic lymphocytes with an intense perforin immunoreactivity are actively interdigitated with apoptotic enterocytes, suggesting the lymphocyte-mediated cell death. In the rat and mouse, no aggregation of phagocytotic macrophages is found in the lamina propria of villus tips. The enterocytes undergoing apoptosis are exfoliated as total, nucleus-containing cells into the lumen. Ultrastructural and cytochemical studies suggest that in the rat and mouse, lamina propria macrophages rather than intraepithelial lymphocytes are involved in cell death of enterocytes. In the human, the aggregation of macrophages is observed in the large intestine, especially the rectum. The intimate relationship between the lamina propria macrophages and the ulcerative colitis is shown experimentally and clinically.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 108, 号 3, p. 167-172, 発行日 1994-03
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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