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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第108巻第5号

1) 消化器癌の腫瘍マーカーアルファフェトプロテインを中心に(シンポジウム 腫瘍マーカーの臨床的意義, 第485回新潟医学会)

http://hdl.handle.net/10191/38260
7aece945-ac3d-4544-86e2-050e592c8a77
名前 / ファイル ライセンス アクション
108(5)_337-341.pdf 108(5)_337-341.pdf (860.0 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-02-10
タイトル
タイトル 1) 消化器癌の腫瘍マーカーアルファフェトプロテインを中心に(シンポジウム 腫瘍マーカーの臨床的意義, 第485回新潟医学会)
タイトル
言語 en
タイトル 1) 消化器癌の腫瘍マーカーアルファフェトプロテインを中心に(シンポジウム 腫瘍マーカーの臨床的意義, 第485回新潟医学会)
言語
言語 jpn
キーワード
主題Scheme Other
主題 alpha-fetoprotein
キーワード
主題Scheme Other
主題 hepatocellular carcinoma
キーワード
主題Scheme Other
主題 fucosylation index
キーワード
主題Scheme Other
主題 glucosaminylation index
キーワード
主題Scheme Other
主題 肝細胞癌
キーワード
主題Scheme Other
主題 アルファフェトプロテイン
キーワード
主題Scheme Other
主題 フコシル化率
キーワード
主題Scheme Other
主題 グルコサミニル化率
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル The Usefulness of the Glycosylation Indices of Human alpha-fetoprotein in the Differential Diagnosis of Neoplastic Diseases of the Liver (Clinical Usefulness of Tumor Markers)
著者 青柳, 豊

× 青柳, 豊

WEKO 120518

青柳, 豊

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著者別名
識別子
識別子 120519
識別子Scheme WEKO
姓名
姓名 Aoyagi, Yutaka
抄録
内容記述タイプ Abstract
内容記述 The degrees of fucosylation (fucosylation index) and glucosaminylation (glucosaminylation index) of alpha-fetoprotein (AFP) were determined in serum samples of 437 patients with hepatocellular carcinoma (HCC), 55 with carcinoma metastatic to the liver from digestive organs and 241 with benign liver diseases. The fucosylation index of AFP in all patients with HCC (39±31%, mean±SD) was significantly higher (P<0.001) than that in patients with benign liver diseases (4±7%). When graded according to a combination of tumor size and serum AFP concentraton, 29 patients with HCC had tumor diameters less than 3 cm and serum concentrations below 400 ng/ml (group B). Twenty-five patients had tumor diameters less than 2 cm and AFP below 1,000 ng/ml (group C) and 15 had tumor diameters less than 2 cm and AFP below 400 ng/ml (group D). The mean fucosylation indices of groups B, C and D were 32±32%, 32±30% and 28±30%, respectively (Fig. 1-B, C and D). These values were higher than those in patients with benign liver diseases with statistical significance. On the other hand, the glucosaminylation index of AFP in patients with carcinoma metastatic to the liver (39±23%) was significantly higher than those in benign liver disease (4±4%) and HCC (2±6%). Thus, the combined information in these two glycosylation indices was useful for the differential diagnosis of neoplastic disases of the liver.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 108, 号 5, p. 337-341, 発行日 1994-05
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
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