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加齢ヌードマウスにおける胸腺外分化Dendritic Epidermal T Cellの同定とその性状の解析
http://hdl.handle.net/10191/43173
http://hdl.handle.net/10191/43173176edb38-5410-4a13-a4c8-df9f871ef6d0
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2016-08-10 | |||||
タイトル | ||||||
タイトル | 加齢ヌードマウスにおける胸腺外分化Dendritic Epidermal T Cellの同定とその性状の解析 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | 加齢ヌードマウスにおける胸腺外分化Dendritic Epidermal T Cellの同定とその性状の解析 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | dendritic epidermal cells (DETC) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | extrathymic differentiation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | athymic nude mice | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | aging | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | flow cytometric analysis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 樹枝状表皮T細胞 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 胸腺外分化 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ヌードマウス | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 加齢 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | フローサイトメトリー | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Identification and Phenotypic Analysis of Extrathymically Differentiated Dendritic Epidermal T Cells in Aged Athymic Nude Mice | |||||
著者 |
富山, 勝博
× 富山, 勝博 |
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著者別名 | ||||||
識別子 | 113095 | |||||
識別子Scheme | WEKO | |||||
姓名 | Tomiyama, Katsuhiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The Epidermis of euthymic mice (+/+) contains a distinct T cell subset called dendritic epidermal T cells (DETC). The majority of these cells are derived from early fetal thymocytes and express invariant γδ T cell receptor (TCR) composed of Vγ3/Vδ1 chain. However, the author found the T cells considered as DETC in aged athymic nude mice (nu/nu). These DETC were consisted of Vγ3^-γδ^+ subset and αβ^+ subset, and demonstrated lower expression of the CD3/TCR complex in comparison with normal Vγ^3+ DETC. The αβ^+ subset was heterogeneous in the Vβ usage. Furthermore, the DETC in aged nu/nu uniformly expressed IL-2Rβ chain even in resting states. These results indicate the age-dependency of the extrathymically maturated DETC, and the phenotypic, possibly functional difference from the thymus-derived DETC. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 110, 号 7, p. 284-293, 発行日 1996-07 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |