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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第110巻第8号

4) 鎌状貧血の遺伝子治療(シンポジウム 遺伝子治療をめぐる諸問題, 第509回新潟医学会)

http://hdl.handle.net/10191/43252
http://hdl.handle.net/10191/43252
feca3552-a3f2-45ef-9049-2d0ef6f28adc
名前 / ファイル ライセンス アクション
110(8)_316-318.pdf 110(8)_316-318.pdf (559.5 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-08-19
タイトル
タイトル 4) 鎌状貧血の遺伝子治療(シンポジウム 遺伝子治療をめぐる諸問題, 第509回新潟医学会)
タイトル
言語 en
タイトル 4) 鎌状貧血の遺伝子治療(シンポジウム 遺伝子治療をめぐる諸問題, 第509回新潟医学会)
言語
言語 jpn
キーワード
主題Scheme Other
主題 gene therapy
キーワード
主題Scheme Other
主題 Sickle cell disease
キーワード
主題Scheme Other
主題 LCR
キーワード
主題Scheme Other
主題 遺伝子治療
キーワード
主題Scheme Other
主題 鎌状貧血
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Gene Therapy for Sickle Cell Disease (Gene Therapy : Advances in Research and Treatment)
著者 古川, 達雄

× 古川, 達雄

WEKO 112777

古川, 達雄

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著者別名
識別子 112778
識別子Scheme WEKO
姓名 Furukawa, Tatsuo
抄録
内容記述タイプ Abstract
内容記述 Sickle cell disease is the one of the molecular disease with a point mutation at the 6th amino in β globin gene. This disease is life threatening because of the obstruction of micro-circulation. Although there are some therapeutic ways for the disease, it is difficult for the patients to obtain long term survival. A lot of patients are waiting for developing a new therapy such as a gene therapy. There are several ways for gene therapy of sickle cell disease, we thought that the expression of γ-globin gene at adult stage might be the best way for the therapy. We have developed the backbone of the vector we would try to use for the gene therapy. The vector may consist; (1) insulator at the both sides, (2) globin gene with the promoter, (3) a strong enhancer such as the LCR (Locus Control Region), (4) the gene element for the in vivo selection, such as a drug resistance gene.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 110, 号 8, p. 316-318, 発行日 1996-08
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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