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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第110巻第12号

開心術後の肺高血圧症に対するNO吸入療法

http://hdl.handle.net/10191/43556
http://hdl.handle.net/10191/43556
010ff56b-2b42-4870-aaa8-0f21c3e08f44
名前 / ファイル ライセンス アクション
110(12)_577-583.pdf 110(12)_577-583.pdf (1.0 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2016-08-31
タイトル
タイトル 開心術後の肺高血圧症に対するNO吸入療法
タイトル
言語 en
タイトル 開心術後の肺高血圧症に対するNO吸入療法
言語
言語 jpn
キーワード
主題Scheme Other
主題 inhaled nitric oxide
キーワード
主題Scheme Other
主題 pulmonary hypertensive crisis
キーワード
主題Scheme Other
主題 congenital heart disease
キーワード
主題Scheme Other
主題 amrinone
キーワード
主題Scheme Other
主題 一酸化窒素吸入
キーワード
主題Scheme Other
主題 肺高血圧クリーゼ
キーワード
主題Scheme Other
主題 先天性心疾患
キーワード
主題Scheme Other
主題 アムリノン
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Inhaled Nitric Oxide : Therapeutic Application for Pulmonary Hypertensive Crisis Following Cardiac Surgery
著者 山本, 和男

× 山本, 和男

WEKO 111632

山本, 和男

Search repository
渡辺, 弘

× 渡辺, 弘

WEKO 111633

渡辺, 弘

Search repository
宮村, 治男

× 宮村, 治男

WEKO 111634

宮村, 治男

Search repository
林, 純一

× 林, 純一

WEKO 111635

林, 純一

Search repository
江口, 昭治

× 江口, 昭治

WEKO 111636

江口, 昭治

Search repository
佐藤, 一範

× 佐藤, 一範

WEKO 111637

佐藤, 一範

Search repository
渡辺, 逸平

× 渡辺, 逸平

WEKO 111638

渡辺, 逸平

Search repository
著者別名
識別子 111639
識別子Scheme WEKO
姓名 Yamamoto, Kazuo
著者別名
識別子 111640
識別子Scheme WEKO
姓名 Watanabe, Hiroshi
著者別名
識別子 111641
識別子Scheme WEKO
姓名 Miyamura, Haruo
著者別名
識別子 111642
識別子Scheme WEKO
姓名 Hayashi, Jun-ichi
著者別名
識別子 111643
識別子Scheme WEKO
姓名 Eguchi, Shoji
著者別名
識別子 111644
識別子Scheme WEKO
姓名 Satoh, Kazunori
著者別名
識別子 111645
識別子Scheme WEKO
姓名 Watanabe, Ippei
抄録
内容記述タイプ Abstract
内容記述 It had not been efficient to manage pulmonary hypertensive crisis(PH crisis)until nitric oxide(NO), an endothelium-derived relaxing factor(EDRF)was applied clinically as pulmonary vasodilators. We experienced two cases of PH crisis after surgery for congenital heart diseases that were refractory to traditional medical therapy. Patient 1:A 7-month-old girl with ventricular septal defect(VSD)and severe pulmonary hypertension(pulmonary artery pressure/systemic pressure;Pp/Ps=0.97 and pulmonary vascular resistance/systemic vascular resistance;Rp/Rs=0.80)underwent VSD closure. In the intensive care unit, NO inhalation was applied for the treatment of PH crisis. Twenty ppm of inhaled NO alleviated pulmonary hypertension without causing systemic hypotension and improved oxygenation. On the second postoperative day, the girl was safely weaned from inhaled NO therapy. Patient 2:A 1-year-old girl with complete endocardial cushion defect(ECD)and pulmonary hypertension(Pp/Ps=0.83, Rp/Rs=0.20)underwent intracardiac repair. She could not be weaned from cardiopulmonary bypass(CPB)because of oversystemic pulmonary hypertension. Following NO inhalation right ventricular pressure/aortic pressure ratio decreased from 1.2 to 0.8, which enabled her to be weaned from CPB. Inhaled NO was terminated after 10 days of low level usage. In conclusion, inhaling low levels of NO provides a useful and safe means to treat PH crisis following surgery for congenital heart disease, and it may help increasing oxygenation by improving ventilation/perfusion ratio.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 110, 号 12, p. 577-583, 発行日 1996-12
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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