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Although it is believed that smoker\u0027s polycythemia is caused by oxygendeficiency induced hypererythropoietinemia, an increase of erythrocyte counts was not demonstrated in the present study. Thinking our data together with the previous reports concerning the impairment of erythrocyte functions such as deformability in smokers, the appearance of macrocytosis was considered to be due to intrinsic abnormality of erythrocytes in smokers. The previous reports concerning abnormal leukocyte function in smokers elicited the idea that increased leukocytes may be also involved in intrinsic abnormality. The abnormalities spreading to both erythrocytes and leukocytes in some of smokers were thought to be derived from pluripotent stem cells. Recent reports concerning high incidence of myelodysplastic syndrome in smokers and macrocytosis as the initial sign of myelodysplastic syndrome, together with our data of macrocytosis in smokers, suggest the progression of some smokers with macrocytosis to myelodysplastic syndrome.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "\u8457\u8005\u5225\u540d", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "107816", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Takahashi, Masuhiro"}]}, {"nameIdentifiers": [{"nameIdentifier": "107817", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Terao, Ayaka"}]}, {"nameIdentifiers": [{"nameIdentifier": "107818", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Murata, Mari"}]}, {"nameIdentifiers": [{"nameIdentifier": "107819", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Shigeno, Naoya"}]}, {"nameIdentifiers": [{"nameIdentifier": "107820", "nameIdentifierScheme": 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