@article{oai:niigata-u.repo.nii.ac.jp:00017040,
 author = {高橋, 益広 and 寺尾, 亜陽佳 and 村田, 真理 and 重野, 直也 and 高橋, 英伸 and 黒羽, 高志 and 増子, 正義 and 鈴木, 訓充 and 古川, 達雄 and 成田, 美和子 and 小池, 正 and 相澤, 義房},
 issue = {10},
 journal = {新潟医学会雑誌, 新潟医学会雑誌},
 month = {Oct},
 note = {The analysis on the association of smoking with hematological findings demonstrated remarkable increases of leukocyte counts, mean corpuscular hemoglobin, and mean corpuscular volume in smokers. Although it is believed that smoker's polycythemia is caused by oxygendeficiency induced hypererythropoietinemia, an increase of erythrocyte counts was not demonstrated in the present study. Thinking our data together with the previous reports concerning the impairment of erythrocyte functions such as deformability in smokers, the appearance of macrocytosis was considered to be due to intrinsic abnormality of erythrocytes in smokers. The previous reports concerning abnormal leukocyte function in smokers elicited the idea that increased leukocytes may be also involved in intrinsic abnormality. The abnormalities spreading to both erythrocytes and leukocytes in some of smokers were thought to be derived from pluripotent stem cells. Recent reports concerning high incidence of myelodysplastic syndrome in smokers and macrocytosis as the initial sign of myelodysplastic syndrome, together with our data of macrocytosis in smokers, suggest the progression of some smokers with macrocytosis to myelodysplastic syndrome.},
 pages = {647--655},
 title = {喫煙による血液異常 : 骨髄異形成症候群との関連について},
 volume = {111},
 year = {1997}
}