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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第112巻第3号

川崎病におけるアンギオテンシンI変換酵素遺伝子多型と冠動脈病変合併に関する検討

http://hdl.handle.net/10191/45761
http://hdl.handle.net/10191/45761
b7ec233b-1b8b-475a-96a3-048396da325c
名前 / ファイル ライセンス アクション
112(3)_144-150.pdf 112(3)_144-150.pdf (986.3 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-01-24
タイトル
タイトル 川崎病におけるアンギオテンシンI変換酵素遺伝子多型と冠動脈病変合併に関する検討
タイトル
言語 en
タイトル 川崎病におけるアンギオテンシンI変換酵素遺伝子多型と冠動脈病変合併に関する検討
言語
言語 jpn
キーワード
主題Scheme Other
主題 Kawasaki disease
キーワード
主題Scheme Other
主題 coronary artery aneurysm
キーワード
主題Scheme Other
主題 ACE polymorphism
キーワード
主題Scheme Other
主題 川崎病
キーワード
主題Scheme Other
主題 冠動脈瘤
キーワード
主題Scheme Other
主題 ACE遺伝子多型
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル Study of Angiotensin I Converting Enzyme Polymorphism in Relation to Coronary Artery Aneurysm Formation in Kawasaki Disease
著者 竹内, 菊博

× 竹内, 菊博

WEKO 106684

竹内, 菊博

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著者別名
識別子 106685
識別子Scheme WEKO
姓名 Takeuchi, Kikuhiro
抄録
内容記述タイプ Abstract
内容記述 ACE (angiotensin I couverting enzyme) gene was examined by polymerase chain reaction (PCR) in 36 subjects who had a past history of Kawasaki disease (16 without coronary aneurysm 20 with coronary aneurysm). A polymorphism in the ACE gene was characterized by three genotypes:two D alleles (genotype DD), two I alleles (genotype II), and heterozygotes allele (genotype DI), Genotype II was found in 65 % of the subjects with aneurysm and 12.5 % of those without aneurysm (p < 0.01, Odds ratio 13.0, 95 % confidence intervals). Although the mechanism of aneurysm formation in Kawasaki disease is unknown, the present study showed that the frequency of II genotype is significantly higher in subjects with Kawasaki disease and coronary aneurysm than in those without aneurysm. These findings suggest that II genotype may contribute to vascular dilatation, contrary to the predisposition of DD genotype to vascular stenosis.
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 112, 号 3, p. 144-150, 発行日 1998-03
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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