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Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats
http://hdl.handle.net/10191/4875
http://hdl.handle.net/10191/48758f2a9f41-c2ca-4355-a20f-18501fe97a54
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
0706081.pdf (4.2 MB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2007-06-08 | |||||
| タイトル | ||||||
| タイトル | Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats | |||||
| タイトル | ||||||
| タイトル | Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Jaw-opening reflex | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Jaw-closing reflex | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Inflammatory pain | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Inflammatory pain | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | journal article | |||||
| 著者 |
Kurose, Masayuki
× Kurose, Masayuki× Yamamura, Kensuke× Noguchi, Makiko× Inoue, Makoto× Ootaki, Sachiko× Yamada, Yoshiaki |
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| 著者別名 | ||||||
| 識別子Scheme | WEKO | |||||
| 識別子 | 4491 | |||||
| 姓名 | 山村, 健介 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Previous studies using the experimental muscle pain model have shown that jaw reflexes and activity patterns of the jaw muscles during movements are altered in the presence of jaw-muscle pain. However, it is still unclear which jaw reflex is more subject to jaw-muscle pain. To clarify this, effects of the application of mustard oil (MO), an inflammatory irritant, into the temporal (jaw-closing) muscle on 1) the jaw-opening reflex evoked by tooth pulp stimulation (TP-evoked JOR) as a nociceptive reflex, 2) jaw-opening reflex evoked by inferior alveolar nerve stimulation as a non-nociceptive reflex, and 3) jaw-closing reflex evoked by trigeminal mesencephalic nucleus stimulation as a proprioceptive reflex were investigated in anesthetized rats. The MO application induced suppression of all reflexes, and the effect on the TP-evoked JOR was more prominent than on the other reflexes. To elucidate the neural mechanisms for these effects, a systemic administration of naloxone following the MO application was conducted. Naloxone not only reversed the MO-induced suppressive effect on the TP-evoked JOR but also facilitated the reflex. The results suggest that nociceptive inputs from orofacial deep tissues alter the gain for jaw reflexes particularly for the nociceptive jaw reflex, and such alteration includes both facilitatory and inhibitory aspects. The results also suggest that pain modulatory mechanisms such as the descending modulatory system play a crucial role in the suppression of nociceptive transmissions related to nociceptive jaw reflex, and under such pathological states, defense reflexes may not be properly evoked. | |||||
| 書誌情報 |
Brain Research en : Brain Research 巻 1041, 号 1, p. 72-86, 発行日 2005-04 |
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| 出版者 | ||||||
| 出版者 | Elsevier Science Ltd. | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00068993 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | info:doi/10.1016/j.brainres.2005.02.003 | |||||
| 著者版フラグ | ||||||
| 値 | author | |||||
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Cite as
Kurose, Masayuki, Yamamura, Kensuke, Noguchi, Makiko, Inoue, Makoto, Ootaki, Sachiko, Yamada, Yoshiaki, 2005, Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats: Elsevier Science Ltd., 72–86 p.
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