{"created":"2021-03-01T06:05:15.833084+00:00","id":1592,"links":{},"metadata":{"_buckets":{"deposit":"55aea3bb-980f-4264-9c6a-cbceae6bc21a"},"_deposit":{"id":"1592","owners":[],"pid":{"revision_id":0,"type":"depid","value":"1592"},"status":"published"},"_oai":{"id":"oai:niigata-u.repo.nii.ac.jp:00001592","sets":["432:477:478","453:454"]},"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"86","bibliographicPageStart":"72","bibliographicVolumeNumber":"1041","bibliographic_titles":[{"bibliographic_title":"Brain Research"},{"bibliographic_title":"Brain Research","bibliographic_titleLang":"en"}]}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Previous studies using the experimental muscle pain model have shown that jaw reflexes and activity patterns of the jaw muscles during movements are altered in the presence of jaw-muscle pain. However, it is still unclear which jaw reflex is more subject to jaw-muscle pain. To clarify this, effects of the application of mustard oil (MO), an inflammatory irritant, into the temporal (jaw-closing) muscle on 1) the jaw-opening reflex evoked by tooth pulp stimulation (TP-evoked JOR) as a nociceptive reflex, 2) jaw-opening reflex evoked by inferior alveolar nerve stimulation as a non-nociceptive reflex, and 3) jaw-closing reflex evoked by trigeminal mesencephalic nucleus stimulation as a proprioceptive reflex were investigated in anesthetized rats. The MO application induced suppression of all reflexes, and the effect on the TP-evoked JOR was more prominent than on the other reflexes. To elucidate the neural mechanisms for these effects, a systemic administration of naloxone following the MO application was conducted. Naloxone not only reversed the MO-induced suppressive effect on the TP-evoked JOR but also facilitated the reflex. The results suggest that nociceptive inputs from orofacial deep tissues alter the gain for jaw reflexes particularly for the nociceptive jaw reflex, and such alteration includes both facilitatory and inhibitory aspects. The results also suggest that pain modulatory mechanisms such as the descending modulatory system play a crucial role in the suppression of nociceptive transmissions related to nociceptive jaw reflex, and under such pathological states, defense reflexes may not be properly evoked.","subitem_description_type":"Abstract"}]},"item_5_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"4491","nameIdentifierScheme":"WEKO"}],"names":[{"name":"山村, 健介"}]}]},"item_5_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Science Ltd."}]},"item_5_relation_14":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"info:doi/10.1016/j.brainres.2005.02.003","subitem_relation_type_select":"DOI"}}]},"item_5_select_19":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_select_item":"author"}]},"item_5_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00068993","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kurose, Masayuki"}],"nameIdentifiers":[{"nameIdentifier":"4485","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamura, Kensuke"}],"nameIdentifiers":[{"nameIdentifier":"4486","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Noguchi, Makiko"}],"nameIdentifiers":[{"nameIdentifier":"4487","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Inoue, Makoto"}],"nameIdentifiers":[{"nameIdentifier":"4488","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Ootaki, Sachiko"}],"nameIdentifiers":[{"nameIdentifier":"4489","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamada, Yoshiaki"}],"nameIdentifiers":[{"nameIdentifier":"4490","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-07-29"}],"displaytype":"detail","filename":"0706081.pdf","filesize":[{"value":"4.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"0706081.pdf","url":"https://niigata-u.repo.nii.ac.jp/record/1592/files/0706081.pdf"},"version_id":"48cd0bb2-3867-4277-aa51-df27b791c22f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Jaw-opening reflex","subitem_subject_scheme":"Other"},{"subitem_subject":"Jaw-closing reflex","subitem_subject_scheme":"Other"},{"subitem_subject":"Inflammatory pain","subitem_subject_scheme":"Other"},{"subitem_subject":"Inflammatory pain","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats"},{"subitem_title":"Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats","subitem_title_language":"en"}]},"item_type_id":"5","owner":"1","path":["454","478"],"pubdate":{"attribute_name":"公開日","attribute_value":"2007-06-08"},"publish_date":"2007-06-08","publish_status":"0","recid":"1592","relation_version_is_last":true,"title":["Modulation of jaw reflexes induced by noxious stimulation to the muscle in anesthetized rats"],"weko_creator_id":"1","weko_shared_id":null},"updated":"2022-12-15T03:34:17.867839+00:00"}