{"_buckets": {"deposit": "eca6a83f-d7ff-4606-906d-41b01cd08d3b"}, "_deposit": {"id": "15723", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "15723"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00015723", "sets": ["456", "543"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Interindividual Differences in Metabolism of Psychotropic Drugs and Drug-Drug Interaction"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1999-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "11-12", "bibliographicPageEnd": "515", "bibliographicPageStart": "507", "bibliographicVolumeNumber": "113", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The development of pharmacokinetics and pharmacogenetics in a last decade has been clarifying the background of remarkable interindividual variability in the metabolism of psychotropic drugs and its clinical significance. This article reviewed the followings: Interindividual variability in plasma concentration of psychotropic drugs, relationship between plasma concentration of psychotropic drugs and its clinical effect, genetic polymorphism of the enzyme which is involved in psychotropic drug metabolism, pharmacokinetic drug-drug interaction, effect of aging on pharmacokinetics, etc.. On the basis of further development of this area in psychiatry, it is desired that more rational psychiatric pharmacotherapy will be established.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "176643", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Someya, Toshiyuki"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "染矢, 俊幸"}], "nameIdentifiers": [{"nameIdentifier": "176642", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-09-30"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "113(11-12)_507-515.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "113(11-12)_507-515.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/15723/files/113(11-12)_507-515.pdf"}, "version_id": "a8e18f5b-56f7-492a-8a09-66a72892286d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "metabolism of psychotropic drugs", "subitem_subject_scheme": "Other"}, {"subitem_subject": "drug-drug interaction", "subitem_subject_scheme": "Other"}, {"subitem_subject": "plasma concentration", "subitem_subject_scheme": "Other"}, {"subitem_subject": "genetic polymorphism", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cytochrome P450", "subitem_subject_scheme": "Other"}, {"subitem_subject": "向精神薬代謝", "subitem_subject_scheme": "Other"}, {"subitem_subject": "薬物相互作用", "subitem_subject_scheme": "Other"}, {"subitem_subject": "血中濃度", "subitem_subject_scheme": "Other"}, {"subitem_subject": "遺伝的多型", "subitem_subject_scheme": "Other"}, {"subitem_subject": "チトクロームP450", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "向精神薬代謝の個体差と薬物相互作用:薬理遺伝学の進歩とその応用について", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "向精神薬代謝の個体差と薬物相互作用:薬理遺伝学の進歩とその応用について"}, {"subitem_title": "向精神薬代謝の個体差と薬物相互作用:薬理遺伝学の進歩とその応用について", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "543"], "permalink_uri": "http://hdl.handle.net/10191/46951", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-03-03"}, "publish_date": "2017-03-03", "publish_status": "0", "recid": "15723", "relation": {}, "relation_version_is_last": true, "title": ["向精神薬代謝の個体差と薬物相互作用:薬理遺伝学の進歩とその応用について"], "weko_shared_id": null}