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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 02 新潟医学会雑誌
  4. 第114巻第2号

ベロ毒素によるTNF -αの産生誘導とカスパーゼ-3の活性化および抗菌剤による抑制効果の検討

http://hdl.handle.net/10191/48765
http://hdl.handle.net/10191/48765
d67955fd-05a3-4017-bf18-41be1e918744
名前 / ファイル ライセンス アクション
114(2)_60-62.pdf 114(2)_60-62.pdf (425.9 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2017-11-17
タイトル
タイトル ベロ毒素によるTNF -αの産生誘導とカスパーゼ-3の活性化および抗菌剤による抑制効果の検討
タイトル
言語 en
タイトル ベロ毒素によるTNF -αの産生誘導とカスパーゼ-3の活性化および抗菌剤による抑制効果の検討
言語
言語 jpn
キーワード
主題Scheme Other
主題 Verotoxin
キーワード
主題Scheme Other
主題 tumor necrosis factor-alpha (TNF-a)
キーワード
主題Scheme Other
主題 caspase-3
キーワード
主題Scheme Other
主題 antimicrobial agent
キーワード
主題Scheme Other
主題 ベロ毒素
キーワード
主題Scheme Other
主題 カスパーゼ-3
キーワード
主題Scheme Other
主題 抗菌剤
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
その他のタイトル
その他のタイトル TNF-a Induction and Caspase-3 Activation by Verotoxin and Effects of Antibiotics on the Apoptosis-Related Factors
著者 吉澤, 麻由子

× 吉澤, 麻由子

WEKO 99924

吉澤, 麻由子

Search repository
百瀬, 能成

× 百瀬, 能成

WEKO 99925

百瀬, 能成

Search repository
普久原, 朝海

× 普久原, 朝海

WEKO 99926

普久原, 朝海

Search repository
林, 正周

× 林, 正周

WEKO 99927

林, 正周

Search repository
堀, 泰彦

× 堀, 泰彦

WEKO 99928

堀, 泰彦

Search repository
森嶋, 計

× 森嶋, 計

WEKO 99929

森嶋, 計

Search repository
著者別名
識別子 99930
識別子Scheme WEKO
姓名 Yoshizawa, Mayuko
著者別名
識別子 99931
識別子Scheme WEKO
姓名 Momose, Takashige
著者別名
識別子 99932
識別子Scheme WEKO
姓名 Fukuhara, Tomomi
著者別名
識別子 99933
識別子Scheme WEKO
姓名 Hayashi, Masachika
著者別名
識別子 99934
識別子Scheme WEKO
姓名 Hori, Yasuhiko
著者別名
識別子 99935
識別子Scheme WEKO
姓名 Morishima, Kazue
抄録
内容記述タイプ Abstract
内容記述 Verotoxin (VT) produced by enterohemorrhagic Escherichia coli (EHEC) is associated with hemolytic uremic syndrome (HUS). VT induces apoptosis in several kinds of tissues and cell lines such as pediatric tubular cells which are considered to be one of the target tissues for HUS. TNF-α, which is induced by VT or EHEC lipopolysaccharide, stimulates the VT-induced apoptosis. ln this study, we have demonstrated that VT1 caused caspase-3 activation in THP-1 cells, and that azithromycin (AZM)significantly inhibited TNF-α induction by VT1 in peripheral blood mononuclear cells. These data provide a useful in vitro model to investigate the mechanism of VT-induced apoptosis through caspase-3, and the suggestion on a possible use of AZM as an immunomodulator to downregurate TNF-α induction
書誌情報 新潟医学会雑誌
en : 新潟医学会雑誌

巻 114, 号 2, p. 60-62, 発行日 2000-02
出版者
出版者 新潟医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 00290440
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AN00182415
著者版フラグ
値 publisher
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