{"_buckets": {"deposit": "6778b570-7169-45fb-baa4-2cb24790b037"}, "_deposit": {"id": "13215", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "13215"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00013215", "sets": ["456", "1041"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Successful Treatment of MRSA Sepsis with Linezolid (ZYVOX^\u003c[○!R]\u003e) : a Case Report"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "174", "bibliographicPageStart": "171", "bibliographicVolumeNumber": "118", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "MRSA感染症に対するlinezolid (ZYVOX^\u003c[○!R]\u003e)の有効性は確認されており,欧米では実地臨床で広く使用されている.一方,本邦ではlinezolidの保険適応はVRE感染症に限定されている.今回,外科手術後のMRSA敗血症に対しlinezolidが著効した1症例を経験したので報告する.症例は73歳男性.膵臓癌に対して幽門輪温存膵頭十二指腸切除術が施行された.術後感染予防のため,術前胆汁培養で検出されたPseudomonas fluorescensに感受性のあるbiapenem(OMEGACIN^\u003c[○!R]\u003e)を手術当日から6日間点滴静注した.術後10病日より39℃台の熱発が出現し,中心静脈栄養カテーテルを抜去するとともにbiapenemをさらに6日間投与した,しかし,39℃台の熱発が持続し,術後10病日の血液培養でMRSAが検出された.術後14病日には血圧低下(80mmHg台)と頻呼吸が出現したため,MRSA敗血症によるショックと診断した.術後15病日からlinezolid (ZYVOX^\u003c[○!R]\u003e)1200mg/日の点滴静注を開始したところ,48時間以内に解熱した.全身状態も速やかに改善し,術後28病日に軽快退院した.本症例の経験および文献的考察から,linezolidは腎機能低下例や自験例の如く時間的猶予のない重症MRSA感染症が良い適応と考えられる.バンコマイシン(VCM)など既存の抗生物質で治療困難なMRSA感染症に対しては,linezolidの救命的な使用も考慮すべきであろう.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "生天目, 信之"}], "nameIdentifiers": [{"nameIdentifier": "87143", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "白井, 良夫"}], "nameIdentifiers": [{"nameIdentifier": "87144", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "畠山, 勝義"}], "nameIdentifiers": [{"nameIdentifier": "87145", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "加藤, 清"}], "nameIdentifiers": [{"nameIdentifier": "87146", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-07"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00004351507.pdf", "filesize": [{"value": "1.3 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1300000.0, "url": {"label": "KJ00004351507.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/13215/files/KJ00004351507.pdf"}, "version_id": "40dbf650-a3d4-45f7-b7e1-3166ce3c14bb"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "linezolid", "subitem_subject_scheme": "Other"}, {"subitem_subject": "メチシリン耐性黄色ブドウ球菌(MRSA)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "バンコマイシン耐性腸球菌(VRE)", "subitem_subject_scheme": "Other"}, {"subitem_subject": "敗血症", "subitem_subject_scheme": "Other"}, {"subitem_subject": "抗菌薬感受性", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "MRSA (メチシリン耐性黄色ブドウ球菌)敗血症に対しlinezolid (ZYVOX^\u003c○!R\u003e)が著効した1例", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "MRSA (メチシリン耐性黄色ブドウ球菌)敗血症に対しlinezolid (ZYVOX^\u003c○!R\u003e)が著効した1例"}, {"subitem_title": "MRSA (メチシリン耐性黄色ブドウ球菌)敗血症に対しlinezolid (ZYVOX^\u003c○!R\u003e)が著効した1例", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "1041"], "permalink_uri": "http://hdl.handle.net/10191/4738", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-05-10"}, "publish_date": "2007-05-10", "publish_status": "0", "recid": "13215", "relation": {}, "relation_version_is_last": true, "title": ["MRSA (メチシリン耐性黄色ブドウ球菌)敗血症に対しlinezolid (ZYVOX^\u003c○!R\u003e)が著効した1例"], "weko_shared_id": null}