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FKN\u306f\u8133\u306a\u3069\u306e\u6b63\u5e38\u7d44\u7e54\u3067\u767a\u73fe\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u304c, \u6b63\u5e38\u7cf8\u7403\u4f53\u306b\u767a\u73fe\u3059\u308bFKN\u306b\u95a2\u3059\u308b\u6587\u732e\u7684\u5831\u544a\u306f\u306a\u3044. \u672c\u7814\u7a76\u3067\u306f, \u6b63\u5e38\u7cf8\u7403\u4f53\u306b\u767a\u73fe\u3057\u3066\u3044\u308bFKN\u306e\u5c40\u5728\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057, \u307e\u305f, \u6b63\u5e38\u3068\u814e\u75be\u60a3\u3067FKN\u306e\u767a\u73fe\u3092\u6bd4\u8f03\u3057, \u7cf8\u7403\u4f53\u306b\u767a\u73fe\u3059\u308bFKN\u306e\u610f\u7fa9\u3092\u691c\u8a0e\u3057\u305f. \u3010\u5bfe\u8c61\u3068\u65b9\u6cd5\u3011WKY\u30e9\u30c3\u30c8\u3092\u7528\u3044, RT-PCR, in situ hybridization (ISH), Western blotting \u304a\u3088\u3073\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u306b\u3088\u308a, FKN\u3068\u305d\u306e\u53d7\u5bb9\u4f53CX3CR1\u306e\u6b63\u5e38\u306e\u814e\u81d3\u306b\u304a\u3051\u308b\u767a\u73fe\u3068\u305d\u306e\u5c40\u5728\u3092\u691c\u8a0e\u3057\u305f. \u307e\u305f, \u534a\u6708\u4f53\u5f62\u6210\u6027\u814e\u708e\u306e\u30e2\u30c7\u30eb\u3067\u3042\u308b\u6297\u7cf8\u7403\u4f53\u57fa\u5e95\u819c (GBM) \u6297\u4f53\u814e\u708e\u3068\u30cd\u30d5\u30ed\u30fc\u30bc\u306e\u30e2\u30c7\u30eb\u3067\u3042\u308bPAN\u814e\u75c7\u306e\u814e\u81d3\u3092\u7528\u3044\u3066, \u6b63\u5e38\u3068\u814e\u75be\u60a3\u306b\u304a\u3051\u308bFKN\u306e\u767a\u73fe\u3092\u6bd4\u8f03\u3057\u305f. \u3010\u7d50\u679c\u3011RT-PCR\u3067, \u30e9\u30c3\u30c8\u306e\u6b63\u5e38\u7cf8\u7403\u4f53\u306b\u304a\u3051\u308bFKN\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u3092\u78ba\u8a8d\u3057\u305f. 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