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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.43 No.4

Specific Effects of 15-Deoxyspergualin on the Fat Metabolism in Partially Hepatectomized Rats

http://hdl.handle.net/10191/33222
http://hdl.handle.net/10191/33222
c2d529ed-7806-4dd5-b764-2d3653b19d5a
名前 / ファイル ライセンス アクション
43(4)_229-232.pdf 43(4)_229-232.pdf (441.7 kB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-08-31
タイトル
タイトル Specific Effects of 15-Deoxyspergualin on the Fat Metabolism in Partially Hepatectomized Rats
タイトル
タイトル Specific Effects of 15-Deoxyspergualin on the Fat Metabolism in Partially Hepatectomized Rats
言語 en
言語
言語 eng
キーワード
主題Scheme Other
主題 lipid
キーワード
主題Scheme Other
主題 cholesterolemia
キーワード
主題Scheme Other
主題 FK506
キーワード
主題Scheme Other
主題 liver
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Date, Kazutoshi

× Date, Kazutoshi

WEKO 53035

Date, Kazutoshi

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Ohtake, Masahiro

× Ohtake, Masahiro

WEKO 53036

Ohtake, Masahiro

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Sakaguchi, Takeo

× Sakaguchi, Takeo

WEKO 53037

Sakaguchi, Takeo

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Aono, Takashi

× Aono, Takashi

WEKO 53038

Aono, Takashi

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Nihei, Kohei

× Nihei, Kohei

WEKO 53039

Nihei, Kohei

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Tsukada, Kazuhiro

× Tsukada, Kazuhiro

WEKO 53040

Tsukada, Kazuhiro

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Hatakeyama, Katsuyoshi

× Hatakeyama, Katsuyoshi

WEKO 53041

Hatakeyama, Katsuyoshi

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抄録
内容記述タイプ Abstract
内容記述 Dynamic changes in fatty parameters in the blood and body were examined after 15-deoxyspergualin (DSG) or FK506 (FK) administration in 65% hepatectomized rats. The body composition of fatty parameters, the Lee-index and retroperitoneal white adipose tissue weight (RPWT) were estimated at 0, 1, 3, 5 and 7 days after hepatectomy. The serum total cholesterol concentration (Tch) and other valves including liver and kidney functions were also estimated. DSG 5 mg/kg increased Tch at 3 days after hepatectomy, then returned to the control level within an additional 2 days. On the other hand, RPWT decreased gradually following DSG injection, and a significanct decrease was observed 7 days after hepatectomy. No difference in Lee-index was seen among the groups. The food and water intake over 9 days and body weight gain after hepatectomy were similar among the three groups. DSG and FK increased blood urea nitrogen (BUN) levels compared with the control. Because the doses of agents utilized have been shown to stimulate liver regeneration, our results suggest that DSG at a dose stimulating liver regeneration produces a higher cholesterol level and promotes the catabolism of adipose tissue more slowly and continuously than FK.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 43, 号 4, p. 229-232, 発行日 1995-12
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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Cite as

Date, Kazutoshi, Ohtake, Masahiro, Sakaguchi, Takeo, Aono, Takashi, Nihei, Kohei, Tsukada, Kazuhiro, Hatakeyama, Katsuyoshi, 1995, Specific Effects of 15-Deoxyspergualin on the Fat Metabolism in Partially Hepatectomized Rats: Niigata University School of Medicine, 229–232 p.

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