{"_buckets": {"deposit": "2840514f-7e2c-4f4c-9771-e67522f94654"}, "_deposit": {"id": "8364", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "8364"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00008364", "sets": ["456", "891"]}, "item_7_alternative_title_1": {"attribute_name": "その他のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "Chimeric Antigen Receptor (Car) : A Novel Cell - Based Therapy for Cancer with Genetically Modified Lymphocytes"}]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "10", "bibliographicPageStart": "7", "bibliographicVolumeNumber": "131", "bibliographic_titles": [{"bibliographic_title": "新潟医学会雑誌"}, {"bibliographic_title": "新潟医学会雑誌", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "キメラ抗原受容体(chimeric antigen receptor: CAR)は単鎖抗体を抗原結合部位とする人工受容体である. ヒトT細胞に遺伝子導入することにより, がん細胞への抗原選択的な障害活性を獲得させる. 筆者らは, 現在米国を中心に臨床開発が進んでいるCD19-CAR遺伝子を開発した. 現在, NK細胞をエフェクターとする戦略や, 固形がんに対する新規CAR開発に取り組んでいる.", "subitem_description_type": "Abstract"}]}, "item_7_full_name_3": {"attribute_name": "著者別名", "attribute_value_mlt": [{"nameIdentifiers": [{"nameIdentifier": "58528", "nameIdentifierScheme": "WEKO"}], "names": [{"name": "Imai, Chihaya"}]}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "新潟医学会"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AN00182415", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00290440", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "今井, 千速"}], "nameIdentifiers": [{"nameIdentifier": "58527", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "131(1)_7-10.pdf", "filesize": [{"value": "414.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 414000.0, "url": {"label": "131(1)_7-10.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/8364/files/131(1)_7-10.pdf"}, "version_id": "f5069189-4355-4a55-8b8b-78dff04d1d3c"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "chimeric antigen receptor", "subitem_subject_scheme": "Other"}, {"subitem_subject": "CD19", "subitem_subject_scheme": "Other"}, {"subitem_subject": "genetic modification", "subitem_subject_scheme": "Other"}, {"subitem_subject": "T cells", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Natural killer cells", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療"}, {"subitem_title": "キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "891"], "permalink_uri": "http://hdl.handle.net/10191/47897", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-09-19"}, "publish_date": "2017-09-19", "publish_status": "0", "recid": "8364", "relation": {}, "relation_version_is_last": true, "title": ["キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療"], "weko_shared_id": null}