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キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療
http://hdl.handle.net/10191/47897
92041152-c705-4ea2-8c1d-808e5fef39f6
名前 / ファイル | ライセンス | アクション | |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-09-19 | |||||
タイトル | ||||||
タイトル | キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | キメラ抗原受容体 (CAR) : 人工受容体遺伝子を導入したリンパ球による新たながん治療 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | chimeric antigen receptor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CD19 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | genetic modification | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | T cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Natural killer cells | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
その他のタイトル | ||||||
その他のタイトル | Chimeric Antigen Receptor (Car) : A Novel Cell - Based Therapy for Cancer with Genetically Modified Lymphocytes | |||||
著者 |
今井, 千速
× 今井, 千速 |
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著者別名 | ||||||
識別子 | ||||||
識別子 | 58528 | |||||
識別子Scheme | WEKO | |||||
姓名 | ||||||
姓名 | Imai, Chihaya | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | キメラ抗原受容体(chimeric antigen receptor: CAR)は単鎖抗体を抗原結合部位とする人工受容体である. ヒトT細胞に遺伝子導入することにより, がん細胞への抗原選択的な障害活性を獲得させる. 筆者らは, 現在米国を中心に臨床開発が進んでいるCD19-CAR遺伝子を開発した. 現在, NK細胞をエフェクターとする戦略や, 固形がんに対する新規CAR開発に取り組んでいる. | |||||
書誌情報 |
新潟医学会雑誌 en : 新潟医学会雑誌 巻 131, 号 1, p. 7-10, 発行日 2017-01 |
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出版者 | ||||||
出版者 | 新潟医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00290440 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00182415 | |||||
著者版フラグ | ||||||
値 | publisher |