{"_buckets": {"deposit": "1cdbef6c-39b2-465e-ba34-ef6bd86587f8"}, "_deposit": {"id": "6640", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6640"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006640"}, "item_7_biblio_info_6": {"attribute_name": "\u66f8\u8a8c\u60c5\u5831", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1989-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3-4", "bibliographicPageEnd": "124", "bibliographicPageStart": "109", "bibliographicVolumeNumber": "37", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "\u6284\u9332", "attribute_value_mlt": [{"subitem_description": "Four patients with myeloproliferative disorders accompanied by myelofibrosis are described. Case 1 was a 49-year-old woman with myelodysplastic syndrome (MDS) terminating in acute leukemia. Case 2 was an 87-year-old man with essential thrombocythemia. Case 3 was a 59-year-old woman with a very unusual clinical record. She was first diagnosed as idiopathic thrombocytopenic purpura. After a splenectomy, her platelet count gradually increased to more than 100 x 10^4/cmm. Fortytwo months after the splenectomy, bone marrow fibrosis was recognized and further 4 years later acute leukemia was diagnosed. Case 4 was a 38-year-old man with Philadelphia chromosome positive chronic myelogenous leukemia. Blast crisis and bone marrow fibrosis developed 28 months after the onset of the symptoms. In all cases, bone marrow aspirations yielded dry taps or only small amounts of particles. Through histological studies of the bone marrows, panmyelosis with a prominent megakaryocytic proliferation and slight or moderate reticulin fibroses were observed. The blast cells in the peripheral blood were not megakaryocytic but granulo-monocytic lineages, because the cells reacted with MCS-2 and were negative for glycoprotein IIb/IIIa complex and glycophorin A by immunoelectron microscopic study. On the other hand, it was considered that the blast cells in case 3, which showed small lymphoblastoid morphology and reacted with HPCA-1, were more primitive cells.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "\u51fa\u7248\u8005", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "\u8457\u8005\u7248\u30d5\u30e9\u30b0", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "\u66f8\u8a8c\u30ec\u30b3\u30fc\u30c9ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "\u8457\u8005", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nemoto, Keiichi"}], "nameIdentifiers": [{"nameIdentifier": "53779", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Satoh, Keiichi"}], "nameIdentifiers": [{"nameIdentifier": "53780", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Umezu, Hajime"}], "nameIdentifiers": [{"nameIdentifier": "53781", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Homma, Keiichi"}], "nameIdentifiers": [{"nameIdentifier": "53782", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ohnishi, Yoshihisa"}], "nameIdentifiers": [{"nameIdentifier": "53783", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "\u30d5\u30a1\u30a4\u30eb\u60c5\u5831", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "37(3-4)_109-124.pdf", "filesize": [{"value": "6.9 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 6900000.0, "url": {"label": "37(3-4)_109-124.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6640/files/37(3-4)_109-124.pdf"}, "version_id": "c23f9fd1-8860-48a3-9585-0b99291a0a11"}]}, "item_language": {"attribute_name": "\u8a00\u8a9e", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "\u8cc7\u6e90\u30bf\u30a4\u30d7", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study", "item_titles": {"attribute_name": "\u30bf\u30a4\u30c8\u30eb", "attribute_value_mlt": [{"subitem_title": "Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study"}, {"subitem_title": "Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["453/456", "471/537/568/648"], "permalink_uri": "http://hdl.handle.net/10191/33545", "pubdate": {"attribute_name": "\u516c\u958b\u65e5", "attribute_value": "2015-10-06"}, "publish_date": "2015-10-06", "publish_status": "0", "recid": "6640", "relation": {}, "relation_version_is_last": true, "title": ["Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study"], "weko_shared_id": null}