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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.37 No.3,4

Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study

http://hdl.handle.net/10191/33545
http://hdl.handle.net/10191/33545
9f7b1b79-0cd4-48c2-8ab1-ffe89fe592b7
名前 / ファイル ライセンス アクション
37(3-4)_109-124.pdf 37(3-4)_109-124.pdf (6.9 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-10-06
タイトル
タイトル Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study
タイトル
言語 en
タイトル Myeloproliferative Disorders and Myelodysplastic Syndrome Accompanied by Myelofibrosis : Histopathology and Immunoelectron Microscopic Study
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Nemoto, Keiichi

× Nemoto, Keiichi

WEKO 53779

Nemoto, Keiichi

Search repository
Satoh, Keiichi

× Satoh, Keiichi

WEKO 53780

Satoh, Keiichi

Search repository
Umezu, Hajime

× Umezu, Hajime

WEKO 53781

Umezu, Hajime

Search repository
Homma, Keiichi

× Homma, Keiichi

WEKO 53782

Homma, Keiichi

Search repository
Ohnishi, Yoshihisa

× Ohnishi, Yoshihisa

WEKO 53783

Ohnishi, Yoshihisa

Search repository
抄録
内容記述タイプ Abstract
内容記述 Four patients with myeloproliferative disorders accompanied by myelofibrosis are described. Case 1 was a 49-year-old woman with myelodysplastic syndrome (MDS) terminating in acute leukemia. Case 2 was an 87-year-old man with essential thrombocythemia. Case 3 was a 59-year-old woman with a very unusual clinical record. She was first diagnosed as idiopathic thrombocytopenic purpura. After a splenectomy, her platelet count gradually increased to more than 100 x 10^4/cmm. Fortytwo months after the splenectomy, bone marrow fibrosis was recognized and further 4 years later acute leukemia was diagnosed. Case 4 was a 38-year-old man with Philadelphia chromosome positive chronic myelogenous leukemia. Blast crisis and bone marrow fibrosis developed 28 months after the onset of the symptoms. In all cases, bone marrow aspirations yielded dry taps or only small amounts of particles. Through histological studies of the bone marrows, panmyelosis with a prominent megakaryocytic proliferation and slight or moderate reticulin fibroses were observed. The blast cells in the peripheral blood were not megakaryocytic but granulo-monocytic lineages, because the cells reacted with MCS-2 and were negative for glycoprotein IIb/IIIa complex and glycophorin A by immunoelectron microscopic study. On the other hand, it was considered that the blast cells in case 3, which showed small lymphoblastoid morphology and reacted with HPCA-1, were more primitive cells.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 37, 号 3-4, p. 109-124, 発行日 1989-12
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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