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Pathological Analysis of Sclerotic Changes of the Glomerulus
http://hdl.handle.net/10191/33497
http://hdl.handle.net/10191/3349757322db1-89e1-428a-b699-f5a3b780dd03
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
38(Suppl.)_55-67.pdf (5.5 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-10-01 | |||||
| タイトル | ||||||
| タイトル | Pathological Analysis of Sclerotic Changes of the Glomerulus | |||||
| タイトル | ||||||
| タイトル | Pathological Analysis of Sclerotic Changes of the Glomerulus | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Iidaka, Kazunari
× Iidaka, Kazunari× Ueda, Yoshihiko× Hirabayashi, Kaoru× Ono, Hidehiko |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Clinico-pathological analysis of focal glomerular sclerosis (FGS) on repeated renal biopsies were made. It was revealed that sizes of capillary lumina in prospective findings of FGS were considered to be larger than those in lipoid nephrosis. (P <0.01) In order to show morphological characteristics of glomeruli in the juxtamedullary cortex of the human kidney, the number of glomeruli and glomerular size in subcapsular and juxtamedullary cortex were compared. Average values obtained by morphometric study per 1 mm^2 were 3.2 glomeruli in the subcapsular and 2.0 glomeruli in the juxtamedullary cortex. Juxtamedullary glomeruli were larger than those in the subcapsular (P<0.05). The luminal diameter of afferent and efferent arteiole in different cortical regions were measured morphologically by scanning electron microscopy using methyl metacrylate casts of renal arterial trees. Afferent arterioles in the subcapsular glomeruli were larger than efferent arterioles. However, efferent arterioles in the juxtamedullary glomeruli were statistically equal to or larger than afferent arterioles. In order to examine anionic sites in the mesangium by intravenous administration of polyethyleneimine (PEI) as a cationic probe, an experimental AN nephrosis model was designed. PEI particles were most numerous in the subendothelial regions in the control. In the group treated with aminonucleoside of puromycin, numbers of PEI particles significantly decreased in each mesangial region, particularly in the paramesangial region. Arterial cushions in the rat kidney were cleary discernible in the arcuate and interlobular arteries but not those in the subcapsular areas. They were stained positively and clearly with colloidal iron. Anionic loss in the mesangial matrix and arterial cushions may be an important etiological factor of glomerulosclerosis. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 38(Supplement), p. 55-67, 発行日 1990-03 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
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| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
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| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
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| 値 | publisher | |||||
