{"_buckets": {"deposit": "b4651784-d8ce-4304-a925-db80112c1c14"}, "_deposit": {"id": "6602", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6602"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006602", "sets": ["456", "641"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1991-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "99", "bibliographicPageStart": "91", "bibliographicVolumeNumber": "39", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Eighteen cases of squamous cell carcinoma (SCC) were examined to reveal its characteristics of differentiation, especially keratinization. Immunohistological procedures were performed with anti-keratin antibodies (Mo-1, K-92, and HKN-5), anti-involucrin, anti-CEA, and anti-epidermal growth factor receptor antibodies. Mo-1 is a monoclonal antibody, produced in the present study, and found to recognize the 58 kd keratin filament of the basal layer of the skin. The results were compared with those of basal cell epithelioma (BCE), Bowen\u0027s disease, and seborrheic keratosis. In keratinized foci of SCC, Bowen\u0027s disease, and seborrheic keratosis, a positive stain of differentiation-associated keratin and involucrin, a negative sign of Mo-1, and a gradually diminished sign of epidermal growth factor receptor were obtained. A membranous stain of CEA and an irregular, \"mosaic\" pattern of HKN-5 were observed in most of the SCC and BCE, occasionally in Bowen\u0027s disease, and rarely in seborrheic keratosis. Though their keratinized regions were morphologically similar, the expression of intra- and extra-cellular materials of the tumor differed among each other.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Fujiwara, Hiroshi"}], "nameIdentifiers": [{"nameIdentifier": "53629", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "39(2)_91-99.pdf", "filesize": [{"value": "3.2 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 3200000.0, "url": {"label": "39(2)_91-99.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6602/files/39(2)_91-99.pdf"}, "version_id": "db310e10-d7d5-482f-9e8c-867efb9851bc"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Aberrant Keratinization in Skin Neoplasms, with Production of Anti-keratin Monoclonal Antibody (Mo-1)", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Aberrant Keratinization in Skin Neoplasms, with Production of Anti-keratin Monoclonal Antibody (Mo-1)"}, {"subitem_title": "Aberrant Keratinization in Skin Neoplasms, with Production of Anti-keratin Monoclonal Antibody (Mo-1)", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "641"], "permalink_uri": "http://hdl.handle.net/10191/33442", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-09-28"}, "publish_date": "2015-09-28", "publish_status": "0", "recid": "6602", "relation": {}, "relation_version_is_last": true, "title": ["Aberrant Keratinization in Skin Neoplasms, with Production of Anti-keratin Monoclonal Antibody (Mo-1)"], "weko_shared_id": null}