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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.39 No.3

Reevaluation of the Localization of Carcinoembryonic Antigen in the Eccrine Gland and Eccrine Gland Tumors by the Use of Monoclonal Antibodies

http://hdl.handle.net/10191/33444
http://hdl.handle.net/10191/33444
b4276c93-f4e9-4adc-bf86-adfafedc0f8b
名前 / ファイル ライセンス アクション
39(3)_111-118.pdf 39(3)_111-118.pdf (5.7 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-09-28
タイトル
タイトル Reevaluation of the Localization of Carcinoembryonic Antigen in the Eccrine Gland and Eccrine Gland Tumors by the Use of Monoclonal Antibodies
タイトル
言語 en
タイトル Reevaluation of the Localization of Carcinoembryonic Antigen in the Eccrine Gland and Eccrine Gland Tumors by the Use of Monoclonal Antibodies
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Ito, Kaoru

× Ito, Kaoru

WEKO 53609

Ito, Kaoru

Search repository
Tezuka, Masaya

× Tezuka, Masaya

WEKO 53610

Tezuka, Masaya

Search repository
Nakamura, Amane

× Nakamura, Amane

WEKO 53611

Nakamura, Amane

Search repository
Ito, Masaaki

× Ito, Masaaki

WEKO 53612

Ito, Masaaki

Search repository
抄録
内容記述タイプ Abstract
内容記述 The localization of carcinoembryonic antigen (CEA) in the eccrine gland apparatus of normal skin and eccrine gland tumors was reevaluated using anti-CEA monoclonal antibodies (MoAbs) which are more specific to colonic CEA. The staining patterns were compared with those of anti-CEA polyclonal antibody (PoAb). The upper portion of the eccrine duct was reactive with all the MoAbs and PoAb. However, the lower duct and secretory portion was weakly or negatively reactive with these MoAbs, while PoAb reacted strongly with these areas. The staining patterns in the eccrine gland tumors implied the direction of differentiation of the tumor cells. The tumor cells which differentiate to the upper eccrine duct showed positive reactivity with MoAbs and PoAb. Those differentiating towards the secretory portion or lower duct reacted strongly with PoAb but weakly or negatively with MoAbs. These results suggest that the antigen which has been regarded as CEA in the skin is not identical to colonic CEA, and shows heterogeneity. Therefore, the presence of some CEA-related antigens was proposed.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 39, 号 3, p. 111-118, 発行日 1991-09
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
著者版フラグ
値 publisher
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