{"_buckets": {"deposit": "1c5cc7e9-d14a-485e-947d-96e8a05abce5"}, "_deposit": {"id": "6536", "owners": [], "pid": {"revision_id": 0, "type": "depid", "value": "6536"}, "status": "published"}, "_oai": {"id": "oai:niigata-u.repo.nii.ac.jp:00006536", "sets": ["456", "632"]}, "item_7_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1993-03", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "31", "bibliographicPageStart": "25", "bibliographicVolumeNumber": "41", "bibliographic_titles": [{"bibliographic_title": "Acta medica et biologica"}, {"bibliographic_title": "Acta medica et biologica", "bibliographic_titleLang": "en"}]}]}, "item_7_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "We examined the denaturing effects of deoxycholate and estrogen-3-monosulfate on antithrombin III (AT III) in vitro. These compounds reduced in parallel both the immunological and anticoagulant activity of AT III at high concentrations, and such denaturing effects were considered to be due to their detergent-like effect. These compounds made AT III heat-labile and reduced the affinity of AT III to sulfated polysaccharides such as heparin attached to agarose gel at lower concentrations, which showed no direct denaturation yet. These results indicate that such compounds bind to a lipophilic portion, which may be involved with the function of AT III.", "subitem_description_type": "Abstract"}]}, "item_7_publisher_7": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Niigata University School of Medicine"}]}, "item_7_select_19": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_select_item": "publisher"}]}, "item_7_source_id_11": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508361", "subitem_source_identifier_type": "NCID"}]}, "item_7_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "05677734", "subitem_source_identifier_type": "ISSN"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Tajima, Yutaka"}], "nameIdentifiers": [{"nameIdentifier": "53390", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tadano, Jutaro"}], "nameIdentifiers": [{"nameIdentifier": "53391", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2019-08-06"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "41(1)_25-31.pdf", "filesize": [{"value": "892.2 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 892200.0, "url": {"label": "41(1)_25-31.pdf", "url": "https://niigata-u.repo.nii.ac.jp/record/6536/files/41(1)_25-31.pdf"}, "version_id": "3cc0e5b5-febb-444b-9733-f3d42bd046cc"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Steroid Derivatives Reduce the Activity of Antithrombin III and the Affinity to Sulfated Polysaccharides", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Steroid Derivatives Reduce the Activity of Antithrombin III and the Affinity to Sulfated Polysaccharides"}, {"subitem_title": "Steroid Derivatives Reduce the Activity of Antithrombin III and the Affinity to Sulfated Polysaccharides", "subitem_title_language": "en"}]}, "item_type_id": "7", "owner": "1", "path": ["456", "632"], "permalink_uri": "http://hdl.handle.net/10191/33314", "pubdate": {"attribute_name": "公開日", "attribute_value": "2015-09-11"}, "publish_date": "2015-09-11", "publish_status": "0", "recid": "6536", "relation": {}, "relation_version_is_last": true, "title": ["Steroid Derivatives Reduce the Activity of Antithrombin III and the Affinity to Sulfated Polysaccharides"], "weko_shared_id": null}