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  1. 0 資料タイプ別
  2. 03 紀要論文
  1. 250 大学院医歯学総合研究科(医)
  2. 20 紀要
  3. 01 Acta medica et biologica
  4. Vol.41 No.3

The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration

http://hdl.handle.net/10191/33325
http://hdl.handle.net/10191/33325
5b2f2ec8-b18c-4618-b9ab-583557711204
名前 / ファイル ライセンス アクション
41(3)_139-148.pdf 41(3)_139-148.pdf (1.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-09-11
タイトル
タイトル The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration
タイトル
タイトル The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration
言語 en
言語
言語 eng
資源タイプ
資源 http://purl.org/coar/resource_type/c_6501
タイプ departmental bulletin paper
著者 Nakadaira, Keiko

× Nakadaira, Keiko

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Nakadaira, Keiko

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内容記述タイプ Abstract
内容記述 This study reinvestigated the effects of an infusion of a monoacetoacetin-glucose mixture on rat liver regeneration in the early phase after partial hepatectomy. Animals were either fed an oral diet ad libitum or administered total parenteral feeding containing a monoacetoacetin-glucose mixture, a 20% glucose solution, or a 5% glucose solution. Six rats from each treatment group were sacrificed at 12, 24, 36, 48, and 72 h after partial hepatectomy. The liver regeneration ratio was used as a parameter for liver regeneration in addition to the labeling index and mitotic index. Body weight change, liver functions, plasma concentrations of energy substrates, and plasma levels of insulin were also measured. The rats receiving a monoacetoacetin-glucose mixture increased their liver regeneration ratio to the same degree as the rats fed orally. Monoacetoacetin infused rats also increased both the labeling index and mitotic index similarly to the rats fed orally, while the latter achieved higher calorie intake than did the rats given monoacetoacetin. Those rats infused with a 20% glucose solution showed a delay in increasing these indices. Although the stimulatory effect of monoacetoacetin on DNA synthesis was not shown in this study, it was confirmed that, in the early phase after partial hepatectomy, a monoacetoacetin-glucose mixture had a more beneficial effect on liver regeneration than glucose alone.
書誌情報 Acta medica et biologica
en : Acta medica et biologica

巻 41, 号 3, p. 139-148, 発行日 1993-09
出版者
出版者 Niigata University School of Medicine
ISSN
収録物識別子タイプ ISSN
収録物識別子 05677734
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00508361
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Nakadaira, Keiko, 1993, The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration: Niigata University School of Medicine, 139–148 p.

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