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The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration
http://hdl.handle.net/10191/33325
http://hdl.handle.net/10191/333255b2f2ec8-b18c-4618-b9ab-583557711204
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
41(3)_139-148.pdf (1.5 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-09-11 | |||||
| タイトル | ||||||
| タイトル | The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration | |||||
| タイトル | ||||||
| タイトル | The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Nakadaira, Keiko
× Nakadaira, Keiko |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study reinvestigated the effects of an infusion of a monoacetoacetin-glucose mixture on rat liver regeneration in the early phase after partial hepatectomy. Animals were either fed an oral diet ad libitum or administered total parenteral feeding containing a monoacetoacetin-glucose mixture, a 20% glucose solution, or a 5% glucose solution. Six rats from each treatment group were sacrificed at 12, 24, 36, 48, and 72 h after partial hepatectomy. The liver regeneration ratio was used as a parameter for liver regeneration in addition to the labeling index and mitotic index. Body weight change, liver functions, plasma concentrations of energy substrates, and plasma levels of insulin were also measured. The rats receiving a monoacetoacetin-glucose mixture increased their liver regeneration ratio to the same degree as the rats fed orally. Monoacetoacetin infused rats also increased both the labeling index and mitotic index similarly to the rats fed orally, while the latter achieved higher calorie intake than did the rats given monoacetoacetin. Those rats infused with a 20% glucose solution showed a delay in increasing these indices. Although the stimulatory effect of monoacetoacetin on DNA synthesis was not shown in this study, it was confirmed that, in the early phase after partial hepatectomy, a monoacetoacetin-glucose mixture had a more beneficial effect on liver regeneration than glucose alone. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 41, 号 3, p. 139-148, 発行日 1993-09 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Nakadaira, Keiko, 1993, The Effect of Ketone Body Infusion on Nutritional Support for Liver Regeneration: Niigata University School of Medicine, 139–148 p.
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