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The Influence of Low Ovarian Response on the Results of In Vitro Fertilization and Embryo Transfer
http://hdl.handle.net/10191/33330
http://hdl.handle.net/10191/3333003e6c730-d5f2-4255-95b7-a010fa3f5971
名前 / ファイル | ライセンス | アクション |
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41(4)_171-176.pdf (736.4 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-09-11 | |||||
タイトル | ||||||
タイトル | The Influence of Low Ovarian Response on the Results of In Vitro Fertilization and Embryo Transfer | |||||
タイトル | ||||||
タイトル | The Influence of Low Ovarian Response on the Results of In Vitro Fertilization and Embryo Transfer | |||||
言語 | en | |||||
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言語 | eng | |||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Hirasawa, Hirofumi
× Hirasawa, Hirofumi |
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内容記述タイプ | Abstract | |||||
内容記述 | Results of in vitro fertilization (IVF) and embryo transfer (ET) were evaluated for different grades of ovarian response stimulated by ovulation inducers. Patients were grouped into low (L group), modest (M group) and high (H group) ovarian responders according to their serum estradiol (E_2) level on the day of HCG (human chrionic gonadotropin) administration, and their results of IVF and ET were compared. The number of subjected cycles totaled 149: 36 in L, 52 in M and 61 in the H group. Although more HCG was administered to the L group than to the M and H groups, the L group had significantly lower numbers of growing follicles and collected oocyte retrieval. The pregnancy rate per oocyte retrieval and per ET was significantly lower in the L group than in the M and H groups. The implantation rate in the L group was also the lowest in these three groups. Another study was carried out with a doubly increased dosage of HMG (human menopausal gonadotropin) given to the 26 low ovarian responders. In this group, serum E_2 level on the day of HCG administration was elevated, and the cancellation rate of oocyte retrieval decreased. As a result, significant increases were observed in numbers of growing follicles, oocyte retrieval, and transferred embryos, with 5 pregnancies thus established. These results suggest that for the further improvement of results in IVF and ET, each patient's ovarian response should be diagnosed before treatment, and according to the diagnosis, methods of ovarian stimulation need to be considered individually. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 41, 号 4, p. 171-176, 発行日 1993-12 |
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出版者 | Niigata University School of Medicine | |||||
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収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
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収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
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値 | publisher |