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Cholera Toxin B Subunit Shows More Intense Affinity to Schwann Cells than Neurons : In Situ and In Vivo Staining
http://hdl.handle.net/10191/33234
http://hdl.handle.net/10191/33234e0c8b95e-11f8-42d9-ba8e-c2e355f9fb24
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
42(1)_19-24.pdf (2.1 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2015-09-04 | |||||
| タイトル | ||||||
| タイトル | Cholera Toxin B Subunit Shows More Intense Affinity to Schwann Cells than Neurons : In Situ and In Vivo Staining | |||||
| タイトル | ||||||
| タイトル | Cholera Toxin B Subunit Shows More Intense Affinity to Schwann Cells than Neurons : In Situ and In Vivo Staining | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源 | http://purl.org/coar/resource_type/c_6501 | |||||
| タイプ | departmental bulletin paper | |||||
| 著者 |
Iwanaga, Toshihiko
× Iwanaga, Toshihiko× Ohtsuka, Hiroyuki |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Conjugates of horseradish peroxidase (HRP) with cholera toxin (CT) are known to be more effective as a probe for studies of neuronal connectivity than HRP only, because of the affinity of CT for GM1 ganglioside which may be richly expressed on neuronal plasma membranes. The present in situ and in vivo staining using CT-fluorescein isothiocyanate (CT-FITC) and CT-HRP demonstrated their intense binding to Schwann cells rather than neurons. Exogenous GM1 successfully competed for the CT binding sites on Schwann cells. This finding suggests the rich existence of GM1 on the Schwann cell surface. | |||||
| 書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 42, 号 1, p. 19-24, 発行日 1994-03 |
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| 出版者 | ||||||
| 出版者 | Niigata University School of Medicine | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 05677734 | |||||
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| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508361 | |||||
| 著者版フラグ | ||||||
| 値 | publisher | |||||
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Cite as
Iwanaga, Toshihiko, Ohtsuka, Hiroyuki, 1994, Cholera Toxin B Subunit Shows More Intense Affinity to Schwann Cells than Neurons : In Situ and In Vivo Staining: Niigata University School of Medicine, 19–24 p.
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