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Studies on the Association between the Anticardiolipin Antibody and Preeclampsia
http://hdl.handle.net/10191/33253
http://hdl.handle.net/10191/3325324503123-228e-46ff-a35d-8b49e74bb44a
名前 / ファイル | ライセンス | アクション |
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-09-04 | |||||
タイトル | ||||||
タイトル | Studies on the Association between the Anticardiolipin Antibody and Preeclampsia | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Studies on the Association between the Anticardiolipin Antibody and Preeclampsia | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源 | http://purl.org/coar/resource_type/c_6501 | |||||
タイプ | departmental bulletin paper | |||||
著者 |
Yasuda, Masako
× Yasuda, Masako× Takakuwa, Koichi× Tanaka, Kenichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In order to evaluate the implication of autoimmune mechanisms in the genesis of preeclampsia, two studies were comprised this work. The one is the assessment of the prevalence of the anticardiolipin antibody in patients with severe preeclampsia. The other is the clinical trial of the prophylaxis of preeclampsia in patients experiencing severe preeclampsia and/or intrauterine fetal growth retardation (IUGR). The positive rate of anticardiolipin antibody in cases with severe preeclampsia was significantly higher than that in normotensive pregnant women. The medication, which consisted of low doses aspirin and a traditional Chinese herbal medicine Sairei-To (Chan-Ling Tang) -which is reported to have glucocorticoid-like effect, was administered to 7 patients who had experienced severe preeclampsia with positive anticardiolipin antibody since the early stage of their new pregnancy. In one case glucocorticoid was also administered. Of seven patients, 5 patients delivered normal sized infants without preeclampsia with the improvement of autoimmune abnormalities. Undersized infants were delivered accompanied by manifestations of preeclampsia in the remaining 2 patients in whom significantly high titers of anticardiolipin antibody continued during their prenatal course. These data indicate that preeclampsia is one of the clinical entities of reproductive autoimmune failure syndrome (RAFS), and that the prediction and prophylaxis of preeclampsia might be possible from the viewpoint of autoimmunity. | |||||
書誌情報 |
Acta medica et biologica en : Acta medica et biologica 巻 42, 号 4, p. 145-149, 発行日 1994-12 |
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出版者 | ||||||
出版者 | Niigata University School of Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 05677734 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508361 | |||||
著者版フラグ | ||||||
値 | publisher |